dc.contributor.author |
Awale S. |
|
dc.contributor.author |
Ueda J.-Y. |
|
dc.contributor.author |
Athikomkulchai S. |
|
dc.contributor.author |
Dibwe D.F. |
|
dc.contributor.author |
Abdelhamed S. |
|
dc.contributor.author |
Yokoyama S. |
|
dc.contributor.author |
Saiki I. |
|
dc.contributor.author |
Miyatake R. |
|
dc.date.accessioned |
2021-04-05T03:33:47Z |
|
dc.date.available |
2021-04-05T03:33:47Z |
|
dc.date.issued |
2012 |
|
dc.identifier.issn |
1633864 |
|
dc.identifier.other |
2-s2.0-84870167887 |
|
dc.identifier.uri |
https://ir.swu.ac.th/jspui/handle/123456789/14246 |
|
dc.identifier.uri |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-84870167887&doi=10.1021%2fnp300596c&partnerID=40&md5=04d0061db3c46e10ce297bb99d0386ab |
|
dc.description.abstract |
Chemical investigation of the stems of Uvaria dac yielded four new highly oxygenated cyclohexene derivatives named uvaridacols E-H (1-4). Their structures were established through NMR and circular dichroism spectroscopic analysis. Uvaridacols E (1), F (2), and H (4) displayed weak preferential cytotoxicity against PANC-1 human pancreatic cancer cells under nutrition-deprived conditions in a concentration-dependent manner, without causing toxicity in normal nutrient-rich conditions. © 2012 The American Chemical Society and American Society of Pharmacognosy. |
|
dc.subject |
antineoplastic agent |
|
dc.subject |
cyclohexene derivative |
|
dc.subject |
herbaceous agent |
|
dc.subject |
unclassified drug |
|
dc.subject |
uvaridacol e |
|
dc.subject |
uvaridacol f |
|
dc.subject |
uvaridacol h |
|
dc.subject |
Annonaceae |
|
dc.subject |
article |
|
dc.subject |
cancer cell |
|
dc.subject |
circular dichroism |
|
dc.subject |
drug structure |
|
dc.subject |
human |
|
dc.subject |
human cell |
|
dc.subject |
nuclear magnetic resonance |
|
dc.subject |
pancreas cancer |
|
dc.subject |
plant stem |
|
dc.subject |
spectroscopy |
|
dc.subject |
Uvaria dac |
|
dc.title |
Uvaridacols E-H, highly oxygenated antiausterity agents from Uvaria dac |
|
dc.type |
Article |
|
dc.rights.holder |
Scopus |
|
dc.identifier.bibliograpycitation |
Journal of Natural Products. Vol 75, No.11 (2012), p.1999-2002 |
|
dc.identifier.doi |
10.1021/np300596c |
|