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Generation of two human iPSC lines (MDCUi001-A and MDCUi001-B) from dermal fibroblasts of a Thai patient with X-linked osteogenesis imperfecta using integration-free Sendai virus

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dc.contributor.author Tongkobpetch S.
dc.contributor.author Rungsiwiwut R.
dc.contributor.author Pruksananonda K.
dc.contributor.author Suphapeetiporn K.
dc.contributor.author Shotelersuk V.
dc.date.accessioned 2021-04-05T03:02:47Z
dc.date.available 2021-04-05T03:02:47Z
dc.date.issued 2019
dc.identifier.issn 18735061
dc.identifier.other 2-s2.0-85069590379
dc.identifier.uri https://ir.swu.ac.th/jspui/handle/123456789/12322
dc.identifier.uri https://www.scopus.com/inward/record.uri?eid=2-s2.0-85069590379&doi=10.1016%2fj.scr.2019.101493&partnerID=40&md5=4e1ce5eee7a33b41e23cb8f86cf3a22a
dc.description.abstract Two clones of human induced pluripotent stem cells (iPSCs) were generated from dermal fibroblasts isolated from a one-year-old Thai patient with X-linked osteogenesis imperfecta. The patient harbored a mutation, p.N459S, in the MBTPS2 gene. The cells were reprogrammed using an integration-free Sendai virus containing KLF4, c-MYC, OCT4 and SOX2. Both of the established iPSC lines (MDCUi001-A and MDCUi001-B) maintained normal karyotype, expressed pluripotent markers and differentiated into all three germ layers. © 2019
dc.subject afp1 protein
dc.subject alpha smooth muscle actin
dc.subject beta tubulin
dc.subject cell marker
dc.subject genomic DNA
dc.subject glyceraldehyde 3 phosphate dehydrogenase
dc.subject kruppel like factor 4
dc.subject membrane bound transcription factor peptidase site 2
dc.subject Myc protein
dc.subject octamer transcription factor 4
dc.subject peptidase
dc.subject rex1 protein
dc.subject tra 1 60 protein
dc.subject tra 1 81 protein
dc.subject transcription factor
dc.subject transcription factor NANOG
dc.subject transcription factor Sox2
dc.subject unclassified drug
dc.subject kruppel like factor
dc.subject kruppel like factor 4
dc.subject Myc protein
dc.subject MYC protein, human
dc.subject SOX2 protein, human
dc.subject transcription factor Sox
dc.subject Article
dc.subject cell clone
dc.subject cell differentiation
dc.subject cell reprogramming technique
dc.subject child
dc.subject controlled study
dc.subject ectoderm
dc.subject embryoid body
dc.subject endoderm
dc.subject human
dc.subject human cell
dc.subject in vitro study
dc.subject induced pluripotent stem cell
dc.subject karyotype
dc.subject male
dc.subject mdcui001 a cell line
dc.subject mdcui001 b cell line
dc.subject mesoderm
dc.subject nonhuman
dc.subject nuclear reprogramming
dc.subject osteogenesis imperfecta
dc.subject pluripotent stem cell line
dc.subject point mutation
dc.subject preschool child
dc.subject priority journal
dc.subject Sendai virus
dc.subject short tandem repeat
dc.subject skin fibroblast
dc.subject Thai (people)
dc.subject cell line
dc.subject cytology
dc.subject fibroblast
dc.subject genetics
dc.subject induced pluripotent stem cell
dc.subject metabolism
dc.subject osteogenesis imperfecta
dc.subject physiology
dc.subject Sendai virus
dc.subject Thailand
dc.subject Cell Differentiation
dc.subject Cell Line
dc.subject Fibroblasts
dc.subject Humans
dc.subject Induced Pluripotent Stem Cells
dc.subject Karyotype
dc.subject Kruppel-Like Transcription Factors
dc.subject Male
dc.subject Osteogenesis Imperfecta
dc.subject Proto-Oncogene Proteins c-myc
dc.subject Sendai virus
dc.subject SOXB1 Transcription Factors
dc.subject Thailand
dc.title Generation of two human iPSC lines (MDCUi001-A and MDCUi001-B) from dermal fibroblasts of a Thai patient with X-linked osteogenesis imperfecta using integration-free Sendai virus
dc.type Article
dc.rights.holder Scopus
dc.identifier.bibliograpycitation Stem Cell Research. Vol 39, (2019)
dc.identifier.doi 10.1016/j.scr.2019.101493


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