Please use this identifier to cite or link to this item: https://ir.swu.ac.th/jspui/handle/123456789/29271
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dc.contributor.authorSripawadkul W.
dc.contributor.authorKhzam R.A.
dc.contributor.authorTang V.
dc.contributor.authorZein M.
dc.contributor.authorDubovy S.R.
dc.contributor.authorGalor A.
dc.contributor.authorKarp C.L.
dc.contributor.otherSrinakharinwirot University
dc.date.accessioned2023-11-15T02:08:14Z-
dc.date.available2023-11-15T02:08:14Z-
dc.date.issued2023
dc.identifier.urihttps://www.scopus.com/inward/record.uri?eid=2-s2.0-85142280891&doi=10.1038%2fs41433-022-02309-7&partnerID=40&md5=659f077819ce61f54c5c25ace0a2ccdd
dc.identifier.urihttps://ir.swu.ac.th/jspui/handle/123456789/29271-
dc.description.abstractPurpose: To describe the anterior segment optical coherence tomography (AS-OCT) appearance of conjunctival papilloma and identify differentiating features from papilliform ocular surface squamous neoplasia (OSSN). Method: A retrospective chart review of individuals clinically diagnosed with conjunctival papilloma (n = 10) or papilliform OSSN (n = 10) based on slit lamp features. Data on demographics, tumour characteristics, and primary treatment were collected. AS-OCT features were assessed including epithelial thickness and reflectivity, a corrugated epithelial surface, presence of an overhanging edge, presence of intrinsic spaces and posterior shadowing. Histopathology was available in 5 papilloma and 3 OSSN specimens. Result: Overall, the majority of individuals in both groups were white males. OSSN lesions were more likely to involve the limbus (80% vs.10%, p = 0.005) and the bulbar conjunctiva (100% vs. 20%, p < 0.001) compared to papillomas. On AS-OCT, maximum epithelial thickness was thicker in papilloma compared to OSSN (936 ± 533 vs. 637 ± 207 µm, p = 0.009). The feature that best differentiated papilloma from OSSN was an overhanging edge (100% vs. 0%, p < 0.001), where the epithelial lesion was seen on top of underlying normal epithelium. Other features more common in papilloma compared to OSSN included a corrugated epithelial surface (70% vs.10%, p = 0.02), the presence of intrinsic spaces (100% vs. 50%, p = 0.03), and posterior shadowing (100% vs. 40%, p = 0.01). Conclusion: AS-OCT shows differentiating features between papilloma and OSSN with an overhanging edge as a distinctive AS-OCT feature of papilloma. © 2022, The Author(s), under exclusive licence to The Royal College of Ophthalmologists.
dc.publisherSpringer Nature
dc.titleAnterior segment optical coherence tomography characteristics of conjunctival papilloma as compared to papilliform ocular surface squamous neoplasia
dc.typeArticle
dc.rights.holderScopus
dc.identifier.bibliograpycitationEye (Basingstoke). Vol 37, No.5 (2023), p.995-1001
dc.identifier.doi10.1038/s41433-022-02309-7
Appears in Collections:Scopus 2023

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