Please use this identifier to cite or link to this item: https://ir.swu.ac.th/jspui/handle/123456789/29269
ชื่อเรื่อง: A novel and easy-to-construct polymeric L-glutamic acid-modified sensor for urinary 1-hydroxypyrene detection: Human biomonitoring of polycyclic aromatic hydrocarbons exposure
ผู้แต่ง: Thangphatthanarungruang J.
Chotsuwan C.
Siangproh W.
Keywords: 1-Hydroxypyrene
Electrochemical sensor
Poly(L-glutamic acid)
Polycyclic aromatic hydrocarbons
Screen-printed graphene electrode
วันที่เผยแพร่: 2023
สำนักพิมพ์: Elsevier B.V.
บทคัดย่อ: 1-Hydroxypyrene (1-OHP), a metabolite of polycyclic aromatic hydrocarbons (PAHs), is a frequently used biomarker for assessing human exposure to PAHs. Therefore, the technology that provides a quick, simple, cost-effective, portable, accurate, precise, and reliable test is still in great demand. To the best of our knowledge, the creation of an electrochemical device based on poly(L-glutamic acid)-modified a screen-printed graphene electrode (poly(L-GA)/SPGE) for 1-OHP detection was described for the first time. The developed sensor was simply and rapidly manufactured via only a single step of electropolymerization. All the concerned parameters and electroanalytical conditions were studied to obtain the best performance of the methodology. Under optimal conditions, the 1-OHP sensing provided a linear range of 1–1000 nM with the limits of detection and quantification of 0.95 and 3.16 nM, respectively. Moreover, this developed sensor was successfully utilized by determining 1-OHP in human urine samples. In comparison with conventional methods, this newly proposed electrochemical methodology might be tremendously valuable for 1-OHP evaluation in environmental and occupational applications, leading to the early detection of illness risk linked to PAHs in the human body. © 2022 Elsevier B.V.
URI: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85137715644&doi=10.1016%2fj.talanta.2022.123929&partnerID=40&md5=b143ffc551d94a832a395971cc6e8b0a
https://ir.swu.ac.th/jspui/handle/123456789/29269
Appears in Collections:Scopus 2023

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