Please use this identifier to cite or link to this item: https://ir.swu.ac.th/jspui/handle/123456789/29086
ชื่อเรื่อง: Electrochemical Capillary Driven Immunoassay for Detection of SARS-CoV-2
ผู้แต่ง: Clark K.M.
Schenkel M.S.
Pittman T.W.
Samper I.C.
Anderson L.B.R.
Khamcharoen W.
Elmegerhi S.
Perera R.
Siangproh W.
Kennan A.J.
Geiss B.J.
Dandy D.S.
Henry C.S.
Keywords: biosensor
electrochemistry
fluidic device
immunoassay
SARS-CoV-2
screen-printed carbon electrodes
biosensor
electrochemistry
fluidic device
immunoassay
SARS-CoV-2
screen-printed carbon electrodes
วันที่เผยแพร่: 2022
สำนักพิมพ์: American Chemical Society
บทคัดย่อ: The COVID-19 pandemic focused attention on a pressing need for fast, accurate, and low-cost diagnostic tests. This work presents an electrochemical capillary driven immunoassay (eCaDI) developed to detect SARS-CoV-2 nucleocapsid (N) protein. The low-cost flow device is made of polyethylene terephthalate (PET) and adhesive films. Upon addition of a sample, reagents and washes are sequentially delivered to an integrated screen-printed carbon electrode for detection, thus automating a full sandwich immunoassay with a single end-user step. The modified electrodes are sensitive and selective for SARS-CoV-2 N protein and stable for over 7 weeks. The eCaDI was tested with influenza A and Sindbis virus and proved to be selective. The eCaDI was also successfully applied to detect nine different SARS-CoV-2 variants, including Omicron. © 2022 American Chemical Society.
URI: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85144551553&doi=10.1021%2facsmeasuresciau.2c00037&partnerID=40&md5=0c6d0f10a1f0841039fc3336496e8ad5
https://ir.swu.ac.th/jspui/handle/123456789/29086
Appears in Collections:Scopus 2022

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