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https://ir.swu.ac.th/jspui/handle/123456789/27221| Title: | Hypoxylonone, a new oxa-bridged seven-membered ring analog from fungus Hypoxylon cf. subgilvum SWUF15-004 |
| Authors: | Jantaharn P. Mongkolthanaruk W. Suwannasai N. Senawong T. Boonmak J. Youngme S. McCloskey S. |
| Keywords: | 8-oxabicyclo[3.2.1]octane cytotoxicity Hypoxylon cf. subgilvum oxa-bridged seven-membered ring |
| Issue Date: | 2022 |
| Publisher: | Taylor and Francis Ltd. |
| Abstract: | A new oxa-bridged seven-membered ring analog, hypoxylonone (1), and thirteen known compounds (2–14) were isolated from fungus Hypoxylon cf. subgilvum SWUF15-004. The structures were elucidated by the analysis of spectroscopic (IR, 1 D and 2 D NMR), HRESIMS and X-ray diffraction (MoKα) data. Several isolated compounds were evaluated for cytotoxicity against four human cancer cell lines (HeLa, HT29, MCF-7, A549). Compound 1 exhibited weak inhibitory effects of the nitric oxide production in RAW264.7 cells. Compounds 8 and 9 exhibited slight cytotoxicity. © 2022 Informa UK Limited, trading as Taylor & Francis Group. |
| URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85138435010&doi=10.1080%2f14786419.2022.2125968&partnerID=40&md5=b5dc24d5493ceff46b7aed645feb0489 https://ir.swu.ac.th/jspui/handle/123456789/27221 |
| ISSN: | 14786419 |
| Appears in Collections: | Scopus 2022 |
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