Please use this identifier to cite or link to this item: https://ir.swu.ac.th/jspui/handle/123456789/17546
ชื่อเรื่อง: Nuchal Skinfold Thickness in Pediatric Brain Tumor Patients
ผู้แต่ง: Peng J.
Boekhoff S.
Eveslage M.
Bison B.
Sowithayasakul P.
Friedrich C.
Müller H.L.
Keywords: adipose tissue
adolescent
Article
body mass
brain tumor
cancer surgery
cardiovascular risk factor
child
childhood cancer
cohort analysis
controlled study
craniopharyngioma
cross-sectional study
diastolic blood pressure
female
human
hypertension
hypothalamus lesion
major clinical study
male
multicenter study (topic)
nuchal skinfold thickness
nuclear magnetic resonance imaging
skinfold thickness
systolic blood pressure
waist circumference
waist to height ratio
วันที่เผยแพร่: 2021
บทคัดย่อ: Background: Severe obesity and tumor relapse/progression have impact on long-term prognosis in pediatric brain tumor patients. Methods: In a cross-sectional study, we analyzed nuchal skinfold thickness (NST) on magnetic-resonance imaging (MRI) follow-up monitoring as a parameter for assessment of nuchal adipose tissue in 177 brain tumor patients (40 World Health Organization (WHO) grade 1–2 brain tumor; 31 grade 3–4 brain tumor; 106 craniopharyngioma), and 53 healthy controls. Furthermore, body mass index (BMI), waist-to-height ratio, caliper-measured skinfold thickness, and blood pressure were analyzed for association with NST. Results: Craniopharyngioma patients showed higher NST, BMI, waist-to-height ratio, and caliper-measured skinfold thickness when compared to other brain tumors and healthy controls. WHO grade 1–2 brain tumor patients were observed with higher BMI, waist circumference and triceps caliper-measured skinfold thickness when compared to WHO grade 3–4 brain tumor patients. NST correlated with BMI, waist-to-height ratio, and caliper-measured skinfold thickness. NST, BMI and waist-to-height ratio were associated with increased blood pressure. In craniopharyngioma patients with hypothalamic involvement/lesion or gross-total resection, rate and degree of obesity were increased. Conclusions: NST could serve as a novel useful marker for regional nuchal adipose tissue. NST is highly associated with body mass and waist-to-height ratio, and easily measurable in routine MRI monitoring of brain tumor patients. Copyright © 2021 Peng, Boekhoff, Eveslage, Bison, Sowithayasakul, Friedrich and Müller.
URI: https://ir.swu.ac.th/jspui/handle/123456789/17546
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85121984682&doi=10.3389%2ffendo.2021.772856&partnerID=40&md5=5ad9ea99c688a1b8e67565bdb207b361
ISSN: 16642392
Appears in Collections:Scopus 1983-2021

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