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Title: | New flavonoids and xanthone from the stem bark of Artocarpus rigidus blume and cytotoxicity |
Authors: | Rattanaburi S. Sriklung K. Watanapokasin R. Mahabusarakam W. |
Keywords: | antineoplastic agent Artocarpus rigidus extract artorigidinone A artorigidinone B artorigidinone C artorixanthone flavonoid gamma geranylapigenin plant extract unclassified drug xanthone derivative flavonoid xanthone derivative antineoplastic activity Article Artocarpus Artocarpus rigidus bark cytotoxicity drug structure drug synthesis human human cell IC50 plant stem spectroscopy SW1353 cell line Artocarpus bark chemical structure Artocarpus Flavonoids Molecular Structure Plant Bark Xanthones |
Issue Date: | 2021 |
Abstract: | Three new flavonoids named artorigidinones A–C and a new xanthone named artorixanthone together with seven known compounds were isolated from the stem bark of Artocarpus rigidus Blume. Their structures were characterized by spectroscopic data. γ-Geranylapigenin exhibited cytotoxicity to a fibroblast-like cell line (SW1353) (IC50 < 0.32 µg/mL) stronger than a standard drug. © 2020 Informa UK Limited, trading as Taylor & Francis Group. |
URI: | https://ir.swu.ac.th/jspui/handle/123456789/17536 https://www.scopus.com/inward/record.uri?eid=2-s2.0-85083580642&doi=10.1080%2f14786419.2020.1753734&partnerID=40&md5=3204482caae80d1d42a1fe2319a687c7 |
ISSN: | 14786419 |
Appears in Collections: | Scopus 1983-2021 |
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