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https://ir.swu.ac.th/jspui/handle/123456789/17531| Title: | A new α-pyrone derivative from Annulohypoxylon stygium SWUF09-030 |
| Authors: | Pimjuk P. Mongkolthanaruk W. Suwannasai N. Senawong T. Tontapha S. Amornkitbumrung V. McCloskey S. |
| Keywords: | pyrone derivative animal Ascomycetes chemical structure mouse RAW 264.7 cell line Animals Ascomycota Mice Molecular Structure Pyrones RAW 264.7 Cells |
| Issue Date: | 2021 |
| Abstract: | A new α-pyrone derivative, namely annulopyronoate (1), together with the known isobenzofuranone, diphenyl ether, sesquiterpene, phenolic and diketopiperazine derivatives (2–12) were isolated from a filamentous fungus Annulohypoxylon stygium SWUF09-030. The structures were determined by analysis of spectroscopic and MS data. The absolute configuration of 1 was determined by comparison of experimental and calculated Electronic Circular Dichroism (ECD) spectra. Compounds 3–5 and 7 exhibited both anti-proliferative effects against HeLa, HT29, HCT116, MCF-7 and Vero cell lines and inhibition of nitric oxide (NO) production in lipopolysaccharide (LPS)-stimulated RAW264.7 macrophage cells. © 2020 Informa UK Limited, trading as Taylor & Francis Group. |
| URI: | https://ir.swu.ac.th/jspui/handle/123456789/17531 https://www.scopus.com/inward/record.uri?eid=2-s2.0-85097763387&doi=10.1080%2f10286020.2020.1856095&partnerID=40&md5=b7085024b51acef721531ad7c610ee2e |
| ISSN: | 10286020 |
| Appears in Collections: | Scopus 1983-2021 |
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