Please use this identifier to cite or link to this item: https://ir.swu.ac.th/jspui/handle/123456789/15398
ชื่อเรื่อง: Method of preparation does not affect the miscibility between steroid hormone and polymethacrylate
ผู้แต่ง: Wiranidchapong C.
Rades T.
Kulvanich P.
Tucker I.G.
Keywords: Differential scanning calorimetry
Drug interactions
Fourier transform infrared spectroscopy
Glass transition
Heating
Hormones
Melting
Polymer blends
Polymer melts
Rapid solidification
Steelmaking
Thermochemistry
Drug-polymer interaction
FTIR
Melting point depression
MTDSC
Polymethacrylate
Steroid hormone
Melting point
วันที่เผยแพร่: 2009
บทคัดย่อ: Miscibility of 17β-estradiol in Eudragit® RS and norethindrone in Eudragit® RS either physical mixes or solid dispersions was determined by modulated temperature differential scanning calorimetry using three heating programs. Heating program I-E revealed the melting point depression of 17β-estradiol in Eudragit® RS as a function of composition, estimated by the Nishi-Wang equation. Heating program II-E disclosed a single glass transition temperature of the blends lying between those of 17β-estradiol and Eudragit® RS, described by the Kwei equation. Heating program I-N demonstrated the reduction of norethindrone melting point when the concentration of Eudragit® RS increased. The parameters determined by the Nishi-Wang and Kwei fits were consistent with the interactions between blend components. No difference in the miscibility and interactions between blend components was observed in the blends prepared by physical mixes and co-evaporation. © 2008 Elsevier B.V. All rights reserved.
URI: https://ir.swu.ac.th/jspui/handle/123456789/15398
https://www.scopus.com/inward/record.uri?eid=2-s2.0-59849091498&doi=10.1016%2fj.tca.2008.12.013&partnerID=40&md5=0fe856594972b083eb69bfa7a180abe7
ISSN: 406031
Appears in Collections:Scopus 1983-2021

Files in This Item:
There are no files associated with this item.


Items in SWU repository are protected by copyright, with all rights reserved, unless otherwise indicated.