Please use this identifier to cite or link to this item: https://ir.swu.ac.th/jspui/handle/123456789/15348
Full metadata record
DC FieldValueLanguage
dc.contributor.authorGovitrapong P.
dc.contributor.authorJitaijamjang W.
dc.contributor.authorChetsawang B.
dc.contributor.authorPhansuwan-Pujito P.
dc.contributor.authorEbadi M.
dc.date.accessioned2021-04-05T04:33:39Z-
dc.date.available2021-04-05T04:33:39Z-
dc.date.issued1998
dc.identifier.issn7423098
dc.identifier.other2-s2.0-0031955063
dc.identifier.urihttps://ir.swu.ac.th/jspui/handle/123456789/15348-
dc.identifier.urihttps://www.scopus.com/inward/record.uri?eid=2-s2.0-0031955063&doi=10.1111%2fj.1600-079X.1998.tb00533.x&partnerID=40&md5=477db2e3ee2855319d57ac6a0902d175
dc.description.abstractPrevious studies in our laboratories have identified a single population of opioid receptors in bovine pineal gland, which we have chosen to characterize further on pinealocytes isolated from the cow and rat pineal gland. The bovine pinealocytes isolated by trypsinization or mechanical manipulation revealed receptor density (B(max)) values of 206.95 ± 131.15 and 220.34 ± 11.80 fmol/mg protein, respectively, and dissociation equilibrium constant (K(d)) values of 1.93 ± 0.48 and 1.96 ± 0.21 nM, respectively. The rat pinealocytes cultured for 7 days exhibited a [3H]diprenorphine binding site of 56 fmol/106 cells. Morphine (100 μM) enhanced the activity of N-acetyltransferase and the level of melatonin in rat pineal gland in culture incubated for 21 hr. The results of these studies suggest that opioidergic receptors exist on pinealocytes and they are involved in stimulating the activity of N-acetyltransferase and the synthesis of melatonin, thereby regulating the physiology of mammalian pineal gland.
dc.subjectacyltransferase
dc.subjectdiprenorphine
dc.subjectmelatonin
dc.subjectopiate receptor
dc.subjectanimal cell
dc.subjectanimal tissue
dc.subjectarticle
dc.subjectcattle
dc.subjectcell isolation
dc.subjectcontrolled study
dc.subjectenzyme activation
dc.subjectnonhuman
dc.subjectpinealocyte
dc.subjectrat
dc.subjectreceptor density
dc.titleExistence and function of opioid receptors on mammalian pinealocytes
dc.typeArticle
dc.rights.holderScopus
dc.identifier.bibliograpycitationJournal of Pineal Research. Vol 24, No.4 (1998), p.201-208
dc.identifier.doi10.1111/j.1600-079X.1998.tb00533.x
Appears in Collections:Scopus 1983-2021

Files in This Item:
There are no files associated with this item.


Items in SWU repository are protected by copyright, with all rights reserved, unless otherwise indicated.