Please use this identifier to cite or link to this item: https://ir.swu.ac.th/jspui/handle/123456789/15273
ชื่อเรื่อง: Seizure threshold in ECT: II. Dose titration vs age and half age methods
ผู้แต่ง: Chanpattana W.
Chakrabhand S.
Techakasem P.
Raksakietisak S.
Keywords: adolescent
adult
age
article
clinical trial
comparative study
electroconvulsive therapy
electrostimulation
female
human
male
methodology
middle aged
paranoid schizophrenia
perceptive threshold
probability
seizure
sensitivity and specificity
sex difference
Adolescent
Adult
Age Factors
Electric Stimulation
Electroconvulsive Therapy
Female
Humans
Male
Middle Aged
Probability
Schizophrenia, Paranoid
Seizures
Sensitivity and Specificity
Sensory Thresholds
Sex Factors
วันที่เผยแพร่: 2000
บทคัดย่อ: Seizure threshold determination is of crucial importance in optimizing electrical stimulus dosage at electroconvulsive therapy (ECT). We measured initial seizure threshold by means of Srinakharinwirot University titration schedule in 106 patients with schizophrenia or schizoaffective disorder, receiving bilateral ECT. Seizure threshold was approximately 106 milli-coulombs on average, and varied 5-fold across patients. Seizure threshold was directly related to age, but inversely related to motor seizure duration. Comparisons of stimulus charge were done with the Age and Half age methods. By using the Half age method, 68 per cent of patients would have seized at the first stimulation and resulted in a closer mean charge to dose-titration method than the Age method. The results may have important clinical implications for stimulus dosing strategy in ECT.
URI: https://ir.swu.ac.th/jspui/handle/123456789/15273
https://www.scopus.com/inward/record.uri?eid=2-s2.0-0034151655&partnerID=40&md5=264e7c227fbf06df8bbd171e2b51f8a3
ISSN: 1252208
Appears in Collections:Scopus 1983-2021

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