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Please use this identifier to cite or link to this item: https://ir.swu.ac.th/jspui/handle/123456789/15226
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dc.contributor.authorSuksamrarn A.
dc.contributor.authorKumpun S.
dc.contributor.authorKirtikara K.
dc.contributor.authorYingyongnarongkul B.
dc.contributor.authorSuksamrarn S.
dc.date.accessioned2021-04-05T04:33:06Z-
dc.date.available2021-04-05T04:33:06Z-
dc.date.issued2002
dc.identifier.issn320943
dc.identifier.other2-s2.0-0036154975
dc.identifier.urihttps://ir.swu.ac.th/jspui/handle/123456789/15226-
dc.identifier.urihttps://www.scopus.com/inward/record.uri?eid=2-s2.0-0036154975&doi=10.1055%2fs-2002-20048&partnerID=40&md5=a1eca6bac96acee5285401d04f3939ef
dc.description.abstractA new iridoid, pedunculariside, together with the known iridoid agnuside were isolated from the butanol extract of Vitex peduncularis stem bark. Both pedunculariside and agnuside showed preferential inhibition of COX-2, with IC50 values of 0.15 ± 0.21 mg/ml and 0.026 ± 0.015 mg/ml respectively, while having only small inhibitory effects on COX-1. Both compounds did not exhibit cytotoxicity against vero cells.
dc.subjectagnuside
dc.subjectantiinflammatory agent
dc.subjectcyclooxygenase 2
dc.subjectiridoid
dc.subjectpedunculariside
dc.subjectplant extract
dc.subjectunclassified drug
dc.subjectVitex peduncularis extract
dc.subjectanimal cell
dc.subjectantiinflammatory activity
dc.subjectarticle
dc.subjectbark
dc.subjectcontrolled study
dc.subjectcytotoxicity
dc.subjectdrug isolation
dc.subjectdrug structure
dc.subjectenzyme inhibition
dc.subjectIC 50
dc.subjectnonhuman
dc.subjectVero cell
dc.subjectAnimals
dc.subjectAnti-Inflammatory Agents
dc.subjectCercopithecus aethiops
dc.subjectCyclooxygenase 1
dc.subjectCyclooxygenase 2
dc.subjectGlucosides
dc.subjectIridoids
dc.subjectIsoenzymes
dc.subjectMagnetic Resonance Spectroscopy
dc.subjectMembrane Proteins
dc.subjectMice
dc.subjectPlant Extracts
dc.subjectProstaglandin-Endoperoxide Synthases
dc.subjectPyrans
dc.subjectVero Cells
dc.subjectVitex
dc.subjectAnimalia
dc.subjectVitex
dc.titleIridoids with anti-inflammatory activity from Vitex peduncularis
dc.typeArticle
dc.rights.holderScopus
dc.identifier.bibliograpycitationPlanta Medica. Vol 68, No.1 (2002), p.72-73
dc.identifier.doi10.1055/s-2002-20048
Appears in Collections:Scopus 1983-2021

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