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Please use this identifier to cite or link to this item: https://ir.swu.ac.th/jspui/handle/123456789/15196
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dc.contributor.authorSuksamrarn S.
dc.contributor.authorSuwannapoch N.
dc.contributor.authorPhakhodee W.
dc.contributor.authorThanuhiranlert J.
dc.contributor.authorRatananukul P.
dc.contributor.authorChimnoi N.
dc.contributor.authorSuksamrarn A.
dc.date.accessioned2021-04-05T04:32:56Z-
dc.date.available2021-04-05T04:32:56Z-
dc.date.issued2003
dc.identifier.issn92363
dc.identifier.other2-s2.0-1542785862
dc.identifier.urihttps://ir.swu.ac.th/jspui/handle/123456789/15196-
dc.identifier.urihttps://www.scopus.com/inward/record.uri?eid=2-s2.0-1542785862&doi=10.1248%2fcpb.51.857&partnerID=40&md5=1836b88c8e26226133b204b8a5a60261
dc.description.abstractPrenylated xanthones, isolated from the fruit hulls and the edible arils and seeds of Garcinia mangostana, were tested for their antituberculosis potential. α- and β-Mangostins and garcinone B exhibited strong inhibitory effect against Mycobacterium tuberculosis with the minimum inhibitory concentration (MIC) value of 6.25 μg/ml. Tri- and tetra-oxygenated xanthones with di-C5 units or with a C5 and a modified C 5 groups are essential for high activities. Substitution in the A and C rings has been shown to modify the bioactivity of the compounds. © 2003 Pharmaceutical Society of Japan.
dc.subjectalpha mangostin
dc.subjectantimycobacterial agent
dc.subjectgarcinia mangostana extract
dc.subjectgarcinone B
dc.subjectmangostin
dc.subjectplant extract
dc.subjecttuberculostatic agent
dc.subjectunclassified drug
dc.subjectxanthone derivative
dc.subjectantiinfective agent
dc.subjectxanthone derivative
dc.subjectantibacterial activity
dc.subjectarticle
dc.subjectdose response
dc.subjectdrug activity
dc.subjectdrug effect
dc.subjectdrug isolation
dc.subjectdrug screening
dc.subjectdrug structure
dc.subjectfruit
dc.subjectGarcinia mangostana
dc.subjectminimum inhibitory concentration
dc.subjectMycobacterium
dc.subjectMycobacterium tuberculosis
dc.subjectnonhuman
dc.subjectoxygenation
dc.subjectplant seed
dc.subjectprenylation
dc.subjectchemistry
dc.subjectfruit
dc.subjectGarcinia mangostana
dc.subjectisolation and purification
dc.subjectmicrobiological examination
dc.subjectprotein processing
dc.subjectAnti-Bacterial Agents
dc.subjectFruit
dc.subjectGarcinia mangostana
dc.subjectMicrobial Sensitivity Tests
dc.subjectProtein Isoprenylation
dc.subjectXanthones
dc.titleAntimycobacterial activity of prenylated xanthones from the fruits of Garcinia mangostana
dc.typeArticle
dc.rights.holderScopus
dc.identifier.bibliograpycitationChemical and Pharmaceutical Bulletin. Vol 51, No.7 (2003), p.857-859
dc.identifier.doi10.1248/cpb.51.857
Appears in Collections:Scopus 1983-2021

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