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Please use this identifier to cite or link to this item: https://ir.swu.ac.th/jspui/handle/123456789/14991
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dc.contributor.authorYingyongnarongkul B.-e.
dc.contributor.authorApiratikul N.
dc.contributor.authorAroonrerk N.
dc.contributor.authorSuksamrarn A.
dc.date.accessioned2021-04-05T04:32:17Z-
dc.date.available2021-04-05T04:32:17Z-
dc.date.issued2006
dc.identifier.issn0960894X
dc.identifier.other2-s2.0-33749434812
dc.identifier.urihttps://ir.swu.ac.th/jspui/handle/123456789/14991-
dc.identifier.urihttps://www.scopus.com/inward/record.uri?eid=2-s2.0-33749434812&doi=10.1016%2fj.bmcl.2006.08.062&partnerID=40&md5=39c9287b3f1fcba02da89c016669696b
dc.description.abstractA library of hydroxycinnamic acid amides (HCAAs) and analogues were synthesized using solid-phase synthesis technique. These compounds were screened for antibacterial against methicillin-resistant Staphylococcus aureus (MRSA) (11 strains) and vancomycin-resistant S. aureus (VRSA) (4 strains). Dihydrocaffeoyl analogues showed activity against VRSA which were better than the reference drugs, vancomycin and oxacillin. These compounds also exhibited antibacterial activity against MRSA, which were more potent than oxacillin. © 2006 Elsevier Ltd. All rights reserved.
dc.subjecthydrocinnamic acid derivative
dc.subjectmeticillin
dc.subjectoxacillin
dc.subjectvancomycin
dc.subjectantibacterial activity
dc.subjectantibiotic resistance
dc.subjectarticle
dc.subjectbacterial strain
dc.subjectcontrolled study
dc.subjectdrug potency
dc.subjectdrug screening
dc.subjectdrug synthesis
dc.subjectmethicillin resistant Staphylococcus aureus
dc.subjectminimum inhibitory concentration
dc.subjectnonhuman
dc.subjectsolid phase synthesis
dc.subjectStaphylococcus aureus
dc.subjectAmides
dc.subjectAnti-Bacterial Agents
dc.subjectCaffeine
dc.subjectCombinatorial Chemistry Techniques
dc.subjectCoumaric Acids
dc.subjectDrug Combinations
dc.subjectEthanol
dc.subjectMethicillin Resistance
dc.subjectOxacillin
dc.subjectStaphylococcus aureus
dc.subjectVancomycin Resistance
dc.subjectmethicillin resistant Staphylococcus aureus
dc.subjectStaphylococcus aureus
dc.titleSolid-phase synthesis and antibacterial activity of hydroxycinnamic acid amides and analogues against methicillin-resistant Staphylococcus aureus and vancomycin-resistant S. aureus
dc.typeArticle
dc.rights.holderScopus
dc.identifier.bibliograpycitationBioorganic and Medicinal Chemistry Letters. Vol 16, No.22 (2006), p.5870-5873
dc.identifier.doi10.1016/j.bmcl.2006.08.062
Appears in Collections:Scopus 1983-2021

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