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https://ir.swu.ac.th/jspui/handle/123456789/14983| Title: | Chemical structures and biological activities of rhamnolipids produced by Pseudomonas aeruginosa B189 isolated from milk factory waste |
| Authors: | Thanomsub B. Pumeechockchai W. Limtrakul A. Arunrattiyakorn P. Petchleelaha W. Nitoda T. Kanzaki H. |
| Keywords: | Anticancer Biological activity Biosurfactant Glycolipid Pseudomonas Rhamnolipid Bacteria Cell culture Lipids Structure (composition) Surface active agents Tumors Bacteriology antineoplastic agent biosurfactant decanoic acid derivative dodecyl sulfate sodium levo rhamnopyranosyl levo rhamnopyranosyl beta hydroxydecanoyl beta hydroxydecanoate levo rhamnopyranosyl levo rhamnopyranosyl beta hydroxydecanoyl beta hydroxydodecanoate lipid polysorbate 80 surfactant unclassified drug Bacteria Bacteriology Cell culture Lipids Structure (composition) Surface active agents Tumors bacterium industrial waste lipid surfactant waste treatment animal cell article bacterium culture bacterium isolate biological activity cancer cell culture cell proliferation chemical structure controlled study human human cell minimum inhibitory concentration nonhuman priority journal Pseudomonas aeruginosa Aedes Animals Antibiotics, Antineoplastic Cell Line Dairy Products Glycolipids Humans Molecular Structure Pseudomonas aeruginosa Surface-Active Agents Insecta Pseudomonas aeruginosa |
| Issue Date: | 2006 |
| Abstract: | The aim of this work was to study chemical structures and biological activities of rhamnolipids produced by Pseudomonas aeruginosa B189 isolated from milk factory waste. The culture produced two biosurfactants, a and b, which showed strong activity and were identified as l-rhamnopyranosyl-l-rhamnopyranosyl-β-hydroxydecanoyl-β-hydroxydecanoate or Rha-Rha C10-C10 and l-rhamnopyranosyl-l-rhamnopyranosyl-β-hydroxydecanoyl-β-hydroxydodecanoate or Rha-Rha C10-C12, respectively. Both compounds exhibited higher surfactant activities tested by the drop collapse test than several artificial surfactants such as SDS and Tween 80. Rhamnolipid a showed significant antiproliferative activity against human breast cancer cell line (MCF-7) at minimum inhibitory concentration (MIC) at 6.25 μg/mL while rhamnolipid b showed MIC against insect cell line C6/36 at 50 μg/mL. © 2005. |
| URI: | https://ir.swu.ac.th/jspui/handle/123456789/14983 https://www.scopus.com/inward/record.uri?eid=2-s2.0-33746227333&doi=10.1016%2fj.biortech.2005.10.029&partnerID=40&md5=21cf570463a46171570ce2b2b2e266ce |
| ISSN: | 9608524 |
| Appears in Collections: | Scopus 1983-2021 |
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