Please use this identifier to cite or link to this item: https://ir.swu.ac.th/jspui/handle/123456789/14953
ชื่อเรื่อง: Paclitaxel and carboplatin for large cell neuroendocrine carcinoma of the uterine cervix
ผู้แต่ง: Tangjitgamol S.
Manusirivithaya S.
Choomchuay N.
Leelahakorn S.
Thawaramara T.
Pataradool K.
Suekwatana P.
Keywords: carboplatin
cisplatin
etoposide
paclitaxel
adrenal metastasis
adult
article
aspiration biopsy
brain metastasis
cancer chemotherapy
cancer regression
cancer staging
cancer survival
case report
clinical feature
computer assisted tomography
disease free interval
drug response
drug substitution
female
histopathology
human
human tissue
hysterectomy
laboratory test
large cell carcinoma
liver metastasis
lymph node metastasis
multiple cycle treatment
neuroendocrine tumor
ovary tumor
recurrent disease
salpingooophorectomy
unspecified side effect
uterine cervix carcinoma
Adult
Antineoplastic Agents
Antineoplastic Agents, Phytogenic
Brain Neoplasms
Carboplatin
Carcinoma, Large Cell
Carcinoma, Neuroendocrine
Chemotherapy, Adjuvant
Combined Modality Therapy
Disease Progression
Fatal Outcome
Female
Humans
Liver Neoplasms
Neoplasm Recurrence, Local
Ovariectomy
Paclitaxel
Uterine Cervical Neoplasms
วันที่เผยแพร่: 2007
บทคัดย่อ: The prognosis of large cell neuroendocrine carcinoma (LCNEC) of the uterine cervix is generally poor despite multimodality of treatments. We report a case of advanced stage cervical LCNEC that showed definite response to paclitaxel/carboplatin, resulting in years of survival. The patient was referred to our institution after undergoing a simple hysterectomy with bilateral salpingo-oophorectomy in her local hospital because of a ruptured metastatic ovarian mass. She declined pelvic radiation treatment, so adjuvant chemotherapy (six cycles of paclitaxel/carboplatin) was given for the residual pelvic nodal diseases. Clinical complete remission was obtained, with a disease-free period of 19 months. Systemic recurrent diseases also showed partial response to the same drug regimen for months with only minimal toxicity. However, she subsequently had progressive diseases in the liver and brain and finally died at 44 months after primary diagnosis and 19 months after recurrent diseases. © 2007 The Authors.
URI: https://ir.swu.ac.th/jspui/handle/123456789/14953
https://www.scopus.com/inward/record.uri?eid=2-s2.0-33847713390&doi=10.1111%2fj.1447-0756.2007.00509.x&partnerID=40&md5=f5ff88a7c610ad00771b079509002ba5
ISSN: 13418076
Appears in Collections:Scopus 1983-2021

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