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dc.contributor.authorWattanapitayakul S.K.
dc.contributor.authorSuwatronnakorn M.
dc.contributor.authorChularojmontri L.
dc.contributor.authorHerunsalee A.
dc.contributor.authorNiumsakul S.
dc.contributor.authorCharuchongkolwongse S.
dc.contributor.authorChansuvanich N.
dc.date.accessioned2021-04-05T04:32:11Z-
dc.date.available2021-04-05T04:32:11Z-
dc.date.issued2007
dc.identifier.issn3788741
dc.identifier.other2-s2.0-33947122236
dc.identifier.urihttps://ir.swu.ac.th/jspui/handle/123456789/14950-
dc.identifier.urihttps://www.scopus.com/inward/record.uri?eid=2-s2.0-33947122236&doi=10.1016%2fj.jep.2006.09.037&partnerID=40&md5=4b8589f68d1c72d28db3f942fc5e21a8
dc.description.abstractThe rhizomes of Kaempferia parviflora (KP) (Zingiberaceae) have been used in Thai traditional medicine for health promotion and for the treatment of digestive disorders and gastric ulcer. This study investigated effect of KP on endothelial function. Studies in human umbilical vein endothelial cells (HUVEC) showed that KP dose-dependently increased nitrite concentrations in culture media after 48 h incubation. eNOS mRNA and protein expression were also enhanced. The induction of eNOS mRNA was detected at 4 h and plateau at 48 h while iNOS expression was not observed. These data demonstrate that KP has a great potential for a supplemental use in vascular endothelial health promotion. © 2006 Elsevier Ireland Ltd. All rights reserved.
dc.subjectalcohol
dc.subjectendothelial nitric oxide synthase
dc.subjectKaempferia parviflora extract
dc.subjectmessenger RNA
dc.subjectnitric oxide
dc.subjectnitrite
dc.subjectplant extract
dc.subjectunclassified drug
dc.subjectarticle
dc.subjectconcentration response
dc.subjectcontrolled study
dc.subjectendothelium cell
dc.subjectgastrointestinal disease
dc.subjectgene expression
dc.subjectgene induction
dc.subjecthealth promotion
dc.subjecthuman
dc.subjecthuman cell
dc.subjectKaempferia parviflora
dc.subjectmedicinal plant
dc.subjectnonhuman
dc.subjectnucleotide sequence
dc.subjectprotein expression
dc.subjectrhizome
dc.subjectstomach ulcer
dc.subjecttraditional medicine
dc.subjectvascular endothelium
dc.subjectZingiberaceae
dc.subjectDose-Response Relationship, Drug
dc.subjectEndothelial Cells
dc.subjectGene Expression Regulation
dc.subjectHumans
dc.subjectMedicine, Oriental Traditional
dc.subjectNitric Oxide
dc.subjectNitric Oxide Synthase Type II
dc.subjectNitric Oxide Synthase Type III
dc.subjectNitrites
dc.subjectPhytotherapy
dc.subjectPlant Extracts
dc.subjectPlants, Medicinal
dc.subjectRhizome
dc.subjectRNA, Messenger
dc.subjectThailand
dc.subjectUmbilical Veins
dc.subjectZingiberaceae
dc.subjectKaempferia parviflora
dc.subjectZingiberaceae
dc.titleKaempferia parviflora ethanolic extract promoted nitric oxide production in human umbilical vein endothelial cells
dc.typeArticle
dc.rights.holderScopus
dc.identifier.bibliograpycitationJournal of Ethnopharmacology. Vol 110, No.3 (2007), p.559-562
dc.identifier.doi10.1016/j.jep.2006.09.037
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