Please use this identifier to cite or link to this item: https://ir.swu.ac.th/jspui/handle/123456789/14542
ชื่อเรื่อง: Expression levels of sex hormone receptors in brains of Japanese medaka, Oryzias latipes (Actinopterygii: Beloniformes: Adrianichthyidae)
ผู้แต่ง: Ngamniyom A.
Sasayama Y.
Keywords: Actinopterygii
Adrianichthyidae
Beloniformes
Oryzias
Oryzias latipes
Oryziinae
Teleostei
วันที่เผยแพร่: 2011
บทคัดย่อ: Background. In teleost fishes, the brain is the target organ for sex steroid hormones. The actions of sex steroid hormones are mediated by their receptors and play an important role in the regulation of endocrine function in the brain. Japanese medaka, Oryzias latipes, is a species widely used in many fields of experimental biology, including neurobiology. In this study, we examined the mRNA expression levels of androgen and estrogen receptors in medaka brains. Materials and methods. The brains of adult fish were separated into three parts (forebrain, midbrain and hindbrain). The expression levels of androgen receptor (AR) and estrogen receptor (ER) β from each part of the brain were determined using a semi-quantitative RT-PCR analysis. Results. AR and ERβ levels in males were higher in the forebrain and midbrain than in the hindbrain. In females, AR and ERβ levels were higher in the forebrain than in the midbrain and hindbrain. AR levels in the forebrain and midbrain of males were higher than those of females. Conversely, there was no difference in ERβ level between males and females. Conclusion. These data on hormone receptors provide the foundation for understanding the molecular basis of AR and ERβ mRNA expression levels in medaka brains. In addition, our results suggest that, in Japanese medaka, AR, but not ERβ, expression may exhibit sexual dimorphisms between males and females in the forebrains and midbrains.
URI: https://ir.swu.ac.th/jspui/handle/123456789/14542
https://www.scopus.com/inward/record.uri?eid=2-s2.0-79953703712&doi=10.3750%2fAIP2011.41.1.05&partnerID=40&md5=db7dfa9b38d8f664bd75af5fbd57715f
ISSN: 1371592
Appears in Collections:Scopus 1983-2021

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