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https://ir.swu.ac.th/jspui/handle/123456789/14519| Title: | Microbial metabolism of α-mangostin isolated from Garcinia mangostana L. |
| Authors: | Arunrattiyakorn P. Suksamrarn S. Suwannasai N. Kanzaki H. |
| Keywords: | antiinfective agent mangostin xanthone derivative article chemical structure chemistry Garcinia mangostana isolation and purification metabolism microbiological examination stereoisomerism Anti-Bacterial Agents Garcinia mangostana Microbial Sensitivity Tests Molecular Structure Stereoisomerism Xanthones Colletotrichum Fungi Garcinia mangostana Glomerella cingulata Mycobacterium tuberculosis Neosartorya Neosartorya spathulata |
| Issue Date: | 2011 |
| Abstract: | α-Mangostin (1), a prenylated xanthone isolated from the fruit hull of Garcinia mangostana L., was individually metabolized by two fungi, Colletotrichum gloeosporioides (EYL131) and Neosartorya spathulata (EYR042), repectively. Incubation of 1 with C. gloeosporioides (EYL131) gave four metabolites which were identified as mangostin 3-sulfate (2), mangostanin 6-sulfate (3), 17,18-dihydroxymangostanin 6-sulfate (4)and isomangostanin 3-sulfate (5). Compound 2 was also formed by incubation with N. spathulata (EYR042). The structures of the isolated compounds were elucidated by spectroscopic data analysis. Of the isolated metabolites, 2 exhibited significant anti-mycobacterial activity against Mycobacterium tuberculosis. © 2011 Elsevier Ltd. All rights reserved. |
| URI: | https://ir.swu.ac.th/jspui/handle/123456789/14519 https://www.scopus.com/inward/record.uri?eid=2-s2.0-79954597523&doi=10.1016%2fj.phytochem.2011.02.007&partnerID=40&md5=d064327319bd37d03baa9d55e46efc80 |
| ISSN: | 319422 |
| Appears in Collections: | Scopus 1983-2021 |
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