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Title: | Bioactive 4-hydroxycinnamide and bioactivities of polyalthia cerasoides |
Authors: | Treeratanapiboon L. Worachartcheewan A. Suksrichavalit T. Kiatfuengfoo R. Prachayasittikul S. Ruchirawat S. Prachayasittikul V. |
Keywords: | 1,1 diphenyl 2 picrylhydrazyl acetic acid ethyl ester alpha tocopherol ampicillin antifungal agent antiinfective agent antioxidant dichloromethane hexane paprazine plant extract plant medicinal product Polyalthia cerasoides extract sitosterol stigmasterol superoxide dismutase triterpene unclassified drug antibacterial activity antifungal activity antioxidant activity article Bacillus cereus Bacillus subtilis Candida albicans controlled study Corynebacterium diphtheriae drug isolation drug structure Gram negative bacterium Gram positive bacterium IC 50 Listeria monocytogenes Micrococcus luteus minimum inhibitory concentration nonhuman Plesiomonas shigelloides Polyalthia Polyalthia cerasoides Pseudomonas stutzeri Saccharomyces cerevisiae Salmonella choleraesuis Salmonella typhimurium Staphylococcus aureus Staphylococcus epidermidis Streptococcus pyogenes Corynebacterium diphtheriae Polyalthia cerasoides |
Issue Date: | 2011 |
Abstract: | Constituents from Polyalthia cerasoides, stem bark methanol extract, were previously documented. This study reports the first isolation of bioactive N-(4-hydroxy-β-phenethyl)-4- hydroxycinnamide (1) from ethyl acetate extract of the plant species including stigmasterol and a mixture of triterpenes from hexane and dichloromethane extracts. Trace essential elements were found in the hexane extract in ppm level. The plant extracts were evaluated for their antimicrobial and antioxidative activities. The dichloromethane extract displayed the highest activity against Corynebacterium diphtheriae NCTC 10356 with MIC of 32 μg/mL, as well as, the highest SOD activity with an IC 50 of 4.51 μg/mL. |
URI: | https://ir.swu.ac.th/jspui/handle/123456789/14482 https://www.scopus.com/inward/record.uri?eid=2-s2.0-80051777986&partnerID=40&md5=db7ddabc5519c986f641923fcb4e56eb |
ISSN: | 16112156 |
Appears in Collections: | Scopus 1983-2021 |
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