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Please use this identifier to cite or link to this item: https://ir.swu.ac.th/jspui/handle/123456789/14402
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dc.contributor.authorNakamura Y.
dc.contributor.authorHe X.
dc.contributor.authorKato H.
dc.contributor.authorWakitani S.
dc.contributor.authorKobayashi T.
dc.contributor.authorWatanabe S.
dc.contributor.authorIida A.
dc.contributor.authorTahara H.
dc.contributor.authorWarman M.L.
dc.contributor.authorWatanapokasin R.
dc.contributor.authorPostlethwait J.H.
dc.date.accessioned2021-04-05T03:34:39Z-
dc.date.available2021-04-05T03:34:39Z-
dc.date.issued2012
dc.identifier.issn2732289
dc.identifier.other2-s2.0-84856260583
dc.identifier.urihttps://ir.swu.ac.th/jspui/handle/123456789/14402-
dc.identifier.urihttps://www.scopus.com/inward/record.uri?eid=2-s2.0-84856260583&doi=10.1007%2fs12010-011-9404-y&partnerID=40&md5=b7c62c3c83efc0cb97c7912a0ba81b75
dc.description.abstractMicroRNA-140 (miR-140) is specifically expressed in developing cartilage tissues. We have previously reported that miR-140 plays an important role during palatal cartilage development by modulating platelet-derived growth factor receptor alpha (pdgfra) in zebrafish. However, the regulatory mechanism of miR-140 in cartilage is still unknown. Using developing zebrafish, sox9a mutant (sox9a-/-) and sox9b mutant (sox9b-/-) zebrafish and SOX9 small interfering RNA in human chondrocytes, T/C-28 cells, we found that miR-140 is regulated by the cartilage master transcription regulator Sox9 in zebrafish and mammalian cells. © 2011 Springer Science+Business Media, LLC.
dc.subjectIn situ hybridization
dc.subjectMicroRNA-140 (miR-140)
dc.subjectRT-PCR
dc.subjectsiRNA
dc.subjectSox9
dc.subjectT/C-28
dc.subjectZebrafish
dc.subjectMammals
dc.subjectPolymerase chain reaction
dc.subjectRNA
dc.subjectTissue
dc.subjectCartilage
dc.subjectmicroRNA
dc.subjectmicroRNA 140
dc.subjectmutant protein
dc.subjectplatelet derived growth factor alpha receptor
dc.subjectsmall interfering RNA
dc.subjecttranscription factor Sox9
dc.subjectunclassified drug
dc.subjectanimal experiment
dc.subjectarticle
dc.subjectcartilage
dc.subjectcartilage cell
dc.subjectcontrolled study
dc.subjecthuman
dc.subjecthuman cell
dc.subjectin situ hybridization
dc.subjectnonhuman
dc.subjectprotein expression
dc.subjectreverse transcription polymerase chain reaction
dc.subjecttranscription regulation
dc.subjectzebra fish
dc.subjectAnimals
dc.subjectBinding Sites
dc.subjectCartilage
dc.subjectChondrocytes
dc.subjectChondrogenesis
dc.subjectEmbryonic Development
dc.subjectGene Expression Regulation, Developmental
dc.subjectHumans
dc.subjectIn Situ Hybridization
dc.subjectMicroRNAs
dc.subjectPhylogeny
dc.subjectProtein Binding
dc.subjectRNA, Small Interfering
dc.subjectSOX9 Transcription Factor
dc.subjectUbiquitin-Protein Ligases
dc.subjectZebrafish
dc.subjectDanio rerio
dc.subjectMammalia
dc.titleSox9 is upstream of microRNA-140 in cartilage
dc.typeArticle
dc.rights.holderScopus
dc.identifier.bibliograpycitationApplied Biochemistry and Biotechnology. Vol 166, No.1 (2012), p.64-71
dc.identifier.doi10.1007/s12010-011-9404-y
Appears in Collections:Scopus 1983-2021

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