Please use this identifier to cite or link to this item: https://ir.swu.ac.th/jspui/handle/123456789/14399
ชื่อเรื่อง: Chemical constituents, and their cytotoxicity, of the rare wood decaying fungus Xylaria humosa
ผู้แต่ง: Sodngam S.
Sawadsitang S.
Suwannasai N.
Mongkolthanaruk W.
Keywords: chevalone B
chevalone C
cytotoxic agent
doxorubicin
ellipticine
epi fiscalin A
epi fiscalin C
ergosterol
ergosterol peroxide
fiscalin A
fungal extract
indole alkaloid
quinazolinone derivative
tamoxifen
terpenoid
tryptoquivaline
unclassified drug
article
breast cancer
cell strain MCF 7
chemical composition
controlled study
cytotoxicity
cytotoxicity assay
fermentation
human
human cell
IC 50
lung small cell cancer
nonhuman
rare species
spectroscopy
squamous cell carcinoma
Thailand
wood decay fungus
Xylaria humosa
Xylariales
Antineoplastic Agents
Cell Line, Tumor
Humans
Wood
Xylariales
วันที่เผยแพร่: 2014
บทคัดย่อ: Samples of Xylaria humosa, a rare species of Xylariaceae, were collected during an investigation into the diversity of the fungus in the Phu Khieo Wildlife Sanctuary, Thailand. Nine compounds were isolated from the species and their structures elucidated by spectroscopic methods. The compounds were ergosterol (1), ergosterol peroxide (2), two meroterpenoids, chevalone B and C (3-4), together with five indole alkaloids, tryptoquivaline L (5), tryptoquivaline M (6), fiscalin A (7), epi-fiscalin A (8) and epi-fiscalin C (9). Compounds 2-9 exhibited variable cytotoxic activity against KB, NCI-H187 and MCF-7 cell lines.
URI: https://ir.swu.ac.th/jspui/handle/123456789/14399
https://www.scopus.com/inward/record.uri?eid=2-s2.0-84894505576&doi=10.1177%2f1934578x1400900205&partnerID=40&md5=4ac2d40ef6dc9694a1f9eb2052ca3bb1
ISSN: 1934578X
Appears in Collections:Scopus 1983-2021

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