Please use this identifier to cite or link to this item: https://ir.swu.ac.th/jspui/handle/123456789/14203
ชื่อเรื่อง: Factors associated with seropositive antibodies to Brucella melitensis in the Nakhon Nayok, Thailand
ผู้แต่ง: Ekpanyaskul C.
Santiwattanakul S.
Tantisiriwat W.
Buppanharun W.
Keywords: adult
agglutination test
article
Brucella melitensis
brucellosis
community program
cross-sectional study
disease surveillance
female
health education
human
infection control
infection prevention
infection risk
major clinical study
male
questionnaire
risk factor
serodiagnosis
seroprevalence
Thailand
Adolescent
Adult
Aged
Animals
Antibodies, Bacterial
Brucellosis
Cattle
Cattle Diseases
Cross-Sectional Studies
Disease Outbreaks
Female
Goat Diseases
Goats
Humans
Logistic Models
Male
Middle Aged
Questionnaires
Risk Factors
Seroepidemiologic Studies
Serologic Tests
Thailand
วันที่เผยแพร่: 2012
บทคัดย่อ: Backgroud: Human brucellosis is a re-emerging disease in Thailand. In 2006, Her Royal Highness Princess Maha Chakri Sirindhorn Medical Center, Nakorn Nayok province had diagnosed three cases of brucellosis which have never been reported in this area. Objective: To conduct an epidemiologic study with the aim of evaluating the sero-prevalence and factors associated with seropositive antibodies to Brucella melitensis among residents who live in the same sub-district of the first index case. Material and Method: In 2007, a study was conducted in Chumpon sub-district, Ongkharak district, Nakhon Nayok province, Thailand where the outbreak took place in the previous year. The 86 subjects were selected from three villages in the present study area. Blood specimens were collected and tested for antibodies for Brucella melitensis using a serum agglutination test. A structural interview questionnaire was used to detect any possible risk factors. A binary logistic regression was utilized for analyzing the statistical data. Results: Of all participants in the present study, 45.35% (95% CI; 34.61-56.08%) had seropositive antibodies to Brucella melitensis. Multivariate analysis indicated that factors associated with seropositive titers were highly related to contact with labored or aborted goats, adjusted odds ratio = 27.16 (95% CI = 1.02-721.53) and the consumption of raw goat products, adjusted odds ratio = 6.27 (95% CI = 1.25-31.36). Conclusion: High seropositive prevalence of Brucella melitenis after the 2006 outbreak was found in the present study. The associated factors of infection are direct contact with infected animals and this is similar with the other outbreak areas in Thailand and the endemic countries. Therefore, local authorities should not only provide the communities with health education, but also conduct continued surveillance in order to help control and prevent the epidemic.
URI: https://ir.swu.ac.th/jspui/handle/123456789/14203
https://www.scopus.com/inward/record.uri?eid=2-s2.0-84876894982&partnerID=40&md5=ae26a313a99d82e7b80e8b91bbbcc38e
ISSN: 1252208
Appears in Collections:Scopus 1983-2021

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