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Title: | A new bisanthraquinone and cytotoxic xanthones from Cratoxylum cochinchinense |
Authors: | Rattanaburi S. Daus M. Watanapokasin R. Mahabusarakam W. |
Keywords: | 1,1',8,8' tetrahydroxy 3,3' dimethoxy 6,6' dimethyl 2' (3 methyl 2 butenyl) (4,4' bianthracene) 9,9',10,10' tetratrone 1,3,6,7 tetrahydroxy 2 (3 methyl 2 butenyl) 5 (3,7 dimethyl 2,6 octadienyl)xanthone 1,3,7 trihydroxy 2 (3 methyl 2 butenyl) 4 (3,7 dimethyl 2,6 octadienyl)xanthone 1,3,7 trihydroxy 2,4 bis(3 methyl 2 butenyl)xanthone 1,6,7 trihydroxy 3 methoxy 2,8 bis(3 methyl 2 butenyl)xanthone 3 geranyloxy 1,7 dihydroxyxanthone 3 isomangostin 7 geranyloxy 1,3 dihydroxyxanthone anthraquinone derivative butharaxanthone celebixanthone cochinchinone C cochinchinoxanthone Cratoxylum cochinchinense extract cudratricusxanthone E cytotoxic agent garcinone D isocudraniaxanthone B mangostin plant extract unclassified drug vismiaquinone C xanthone derivative article breast cancer cancer cell culture cell proliferation cell viability assay Clusiaceae Cratoxylum cochinchinense cytotoxicity human human cell IC 50 plant stem squamous cell carcinoma Cratoxylum cochinchinense bisanthraquinone Cratoxylum cochinchinense cytotoxicity xanthones Anthraquinones Antineoplastic Agents, Phytogenic Clusiaceae Drug Screening Assays, Antitumor Female Humans Molecular Structure Plant Stems Xanthones |
Issue Date: | 2014 |
Abstract: | A new bisanthraquinone has been isolated from the stems of Cratoxylum cochinchinense together with vismiaquinone C and 16 known xanthones. Their structures were characterised by using spectroscopic methods. Two of the isolated compounds are modified xanthones (6 and 15) and exhibited strong cytotoxicity against human epidermoid carcinoma (A341: IC50 2.01, 1.78 g/mL) and human breast cancer cell lines (SKBR3: IC50 1.54, 0.69 g/mL). © 2014 Taylor & Francis. |
URI: | https://ir.swu.ac.th/jspui/handle/123456789/14133 https://www.scopus.com/inward/record.uri?eid=2-s2.0-84899480252&doi=10.1080%2f14786419.2014.886212&partnerID=40&md5=01181238dff0b06fc349a3310289e909 |
ISSN: | 14786419 |
Appears in Collections: | Scopus 1983-2021 |
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