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Title: | Autophagy in epithelial homeostasis and defense |
Authors: | Sukseree S. Eckhart L. Tschachler E. Watanapokasin R. |
Keywords: | adaptor protein autophagy protein 5 autophagy protein 7 cytoplasm protein green fluorescent protein hybrid protein NBR1 protein nucleotide binding oligomerization domain like receptor pattern recognition receptor protein p62 retinoic acid inducible protein I unclassified drug article autophagosome autophagy cell differentiation cell function cell survival cytoplasm epidermis epithelium cell gene deletion innate immunity intestine epithelium keratinocyte knockout gene lung alveolus epithelium lysosome mouse nonhuman protein aggregation protein binding protein degradation protein processing protein ubiquitinylation skin appendage stratum corneum stress transgenic mouse ultraviolet A radiation ultraviolet B radiation virus immunity |
Issue Date: | 2013 |
Abstract: | Autophagy delivers protein aggregates, damaged organelles and intracellular microorganisms to the lysosome for degradation. The epidermis and other epithelia show significant levels of autophagy, however, the functions of autophagy in these tissues have remained elusive until recently. Here we review the experimental approaches for the investigation of autophagy in epithelia and discuss the roles of autophagy in epithelial cells with a focus on epidermal keratinocytes and thymic epithelial cells. |
URI: | https://ir.swu.ac.th/jspui/handle/123456789/14062 https://www.scopus.com/inward/record.uri?eid=2-s2.0-84884299292&partnerID=40&md5=c34ede7d7fcefaeb4ee3f1b9e22e7a69 |
ISSN: | 19450494 |
Appears in Collections: | Scopus 1983-2021 |
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