1. Srinakharinwirot University Institutional Repository
  2. Articles from Academic Databases : SCOPUS
  3. Scopus 1983-2021
Please use this identifier to cite or link to this item: https://ir.swu.ac.th/jspui/handle/123456789/13968
Full metadata record
DC FieldValueLanguage
dc.contributor.authorPingaew R.
dc.contributor.authorWorachartcheewan A.
dc.contributor.authorPrachayasittikul V.
dc.contributor.authorPrachayasittikul S.
dc.contributor.authorRuchirawat S.
dc.contributor.authorPrachayasittikul V.
dc.date.accessioned2021-04-05T03:32:46Z-
dc.date.available2021-04-05T03:32:46Z-
dc.date.issued2013
dc.identifier.issn15701808
dc.identifier.other2-s2.0-84887864374
dc.identifier.urihttps://ir.swu.ac.th/jspui/handle/123456789/13968-
dc.identifier.urihttps://www.scopus.com/inward/record.uri?eid=2-s2.0-84887864374&doi=10.2174%2f15701808113109990004&partnerID=40&md5=a3eee064f49f651dd797425acaef207d
dc.description.abstractMetal complexes of 8-aminoquinoline (8AQ) derivatives were reported. This study presents a series of synthesized transition metal complexes of mixed ligands 8AQ-5-iodouracils (1-3) and 8AQ-5-nitrouracil (4-6) which have been investigated for their antioxidative and cytotoxic activities, as well as, powder X-ray diffraction patterns. Ni complex of 8AQ-5-nitrouracil (6) exerted significant cytotoxicity against MOLT-3 cell and superoxide scavenging activity. The results demonstrate an application of 8AQ molecule as a potential ligand for new bioactive compounds. ©2013 Bentham Science Publishers.
dc.subject8 aminoquinoline derivative
dc.subjectcopper complex
dc.subjectdoxorubicin
dc.subjectetoposide
dc.subjectligand
dc.subjectmanganese derivative
dc.subjectmetal complex
dc.subjectnickel complex
dc.subjectreactive nitrogen species
dc.subjectreactive oxygen metabolite
dc.subjectsuperoxide
dc.subjectsuperoxide dismutase
dc.subjecttransition element
dc.subjecturacil derivative
dc.subjectantioxidant activity
dc.subjectarticle
dc.subjectcancer cell culture
dc.subjectcomplex formation
dc.subjectcontrolled study
dc.subjectdrug cytotoxicity
dc.subjectdrug synthesis
dc.subjecthuman
dc.subjecthuman cell
dc.subjectIC 50
dc.subjectinfrared spectroscopy
dc.subjectpriority journal
dc.subjectstructure activity relation
dc.subjectX ray powder diffraction
dc.titleTransition metal complexes of 8-aminoquinoline-5-substituted uracils with antioxidative and cytotoxic activities
dc.typeArticle
dc.rights.holderScopus
dc.identifier.bibliograpycitationLetters in Drug Design and Discovery. Vol 10, No.9 (2013), p.859-864
dc.identifier.doi10.2174/15701808113109990004
Appears in Collections:Scopus 1983-2021

Files in This Item:
There are no files associated with this item.
Show simple item record


Items in SWU repository are protected by copyright, with all rights reserved, unless otherwise indicated.