Please use this identifier to cite or link to this item: https://ir.swu.ac.th/jspui/handle/123456789/13633
ชื่อเรื่อง: Epidemiology of candida infections in HRH princess maha chakri sirindhorn medical center, srinakharinwirot university
ผู้แต่ง: Tantisiriwat W.
Santiwattanakul S.
Keywords: amphotericin B
fluconazole
amphotericin B
antifungal agent
fluconazole
antibiotic sensitivity
Article
Candida albicans
Candida glabrata
Candida parapsilosis
Candida tropicalis
Candida zeylanoides
candidemia
candidiasis
Clavispora lusitaniae
Kluyveromyces marxianus
Meyerozyma guilliermondii
minimum inhibitory concentration
nonhuman
prospective study
sensitivity analysis
Candida
candidiasis
human
isolation and purification
microbial sensitivity test
procedures
United States
university hospital
Academic Medical Centers
Amphotericin B
Antifungal Agents
Candida
Candida albicans
Candidiasis
Fluconazole
Humans
Microbial Sensitivity Tests
Prospective Studies
United States
วันที่เผยแพร่: 2015
บทคัดย่อ: Objective: To identify the epidemiology of candida isolations in HRH Princess Maha Chakri Sirindhorn Medical Center and the sensitivity of all candida species to fluconazole. Material and Method: Two hundred of Candida albicans and other Candida species from clinical specimens were collected from microbiological department between January 2010 and April 2012. All Candida were identified by standard methods and the sensitivity of fluconazole was tested by using fluconazole E test test. Results: There were 8 species of Candida in this study including: C. albicans (n = 94), C. tropicalis (n = 66), C. glabrata (n = 11), C. guilliermondii (n = 10), C. parapsilosis (n = 9), C. zeylanoides (n = 4), C. keyfr (C. pseudotropicalis) (n = 2), C. lusitaniae (n = 1), Candida species (n = 3). The percentage of non-albicans Candida spp. was slightly higher than C. albicans (53% vs. 47%). C. tropicalis was identified as the highest percentage of all non-albicans Candida spp. Fluconazole resistant strains were detected among C. albicans (35.71%), C. tropicalis (13.85%), C. guilliermondii (20.0%), and C. zeylanoides (50.0%). The common spp. with highest percentage of resistant strain was C. albicans. Conclusion: Fluconazole could be used as the first-line antifungal for candidiasis at HRH Princess Maha Chakri Sirindhorn Medical Center. Empirical treatment with amphotericin B and stepping down to fluconazole when sensitivity suggested might be the recommendation for severe cases in our setting. © 2015, Medical Association of Thailand. All rights reserved.
URI: https://ir.swu.ac.th/jspui/handle/123456789/13633
https://www.scopus.com/inward/record.uri?eid=2-s2.0-84957716993&partnerID=40&md5=60b202cacabbfe993878296c9877b11d
ISSN: 1252208
Appears in Collections:Scopus 1983-2021

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