Antiacne-causing bacteria, antioxidant, anti-Tyrosinase, anti-elastase and anti-collagenase activities of blend essential oil comprising rose, bergamot and patchouli oils

Abstract

Blended essential oil comprising rose, bergamot and patchouli (RBP) oils with the volume ratio of 6:3:1, respectively have been tested for various biological activities. The blended oil showed antimicrobial activity against Propionibacterium acnes and Staphylococcus epidermidis with minimum inhibitory concentration (MIC) of 0.003125 %v/v and 0.125 %v/v, respectively. For antioxidant, blended oil showed the half inhibitory concentration (IC50) at 0.67 %v/v and 0.14 %v/v while tested with 2,2-diphenyl-1-picrylhydrazyl (DPPH) and 2,2-Azinobis(3-ethylbenzothiazoline-6 sulphonic acid) (ATBS) assays, respectively. Blended oil also has anti-Tyrosinase activity with 45±4.6%tyrosinase inhibition at 4 mg/mL concentration using modified dopachrome method. However it has no activity on anti-collagenase and anti-elastase. © 2018 Natural Product Incorporation. All rights reserved.