Please use this identifier to cite or link to this item: https://ir.swu.ac.th/jspui/handle/123456789/12809
ชื่อเรื่อง: Development of a gallic acid-loaded chitosan and polyvinyl alcohol hydrogel composite: Release characteristics and antioxidant activity
ผู้แต่ง: Thanyacharoen T.
Chuysinuan P.
Techasakul S.
Nooeaid P.
Ummartyotin S.
Keywords: chitosan
gallic acid
polyvinyl alcohol
tetraethoxysilane
1,1-diphenyl-2-picrylhydrazyl
antioxidant
biphenyl derivative
chitosan
gallic acid
picric acid
polyethylene glycol dimethacrylate hydrogel
polyvinyl alcohol
polyvinyl alcohol hydrogel
scavenger
antioxidant activity
Article
controlled study
degradation
differential scanning calorimetry
DPPH radical scavenging assay
drug delivery system
drug release
drug stability
encapsulation
Fourier transform infrared photoacoustic spectroscopy
heat tolerance
hydrogel
miscibility
physical chemistry
scanning electron microscopy
chemistry
infrared spectroscopy
synthesis
Antioxidants
Biphenyl Compounds
Chitosan
Drug Delivery Systems
Free Radical Scavengers
Gallic Acid
Hydrogel, Polyethylene Glycol Dimethacrylate
Picrates
Polyvinyl Alcohol
Spectroscopy, Fourier Transform Infrared
วันที่เผยแพร่: 2018
บทคัดย่อ: The physico-chemical properties of a chitosan and polyvinyl alcohol (CS/PVA)-based hydrogel composite were investigated. Tetraethyl orthosilicate (TEOS) was employed as a crosslinking agent. The results indicated that the chitosan-based composite presented a thermal resistance up to 200 °C. The structural properties, which were evaluated using FTIR and DSC, showed good miscibility between chitosan and polyvinyl alcohol. SEM presented a compact and homogeneous structure. The release profile of the chitosan-based hydrogel composite was investigated using gallic acid (GA). It showed high antioxidant activities, which were monitored using DPPH radical scavenging. Diffusion of water into the chitosan-based hydrogel was assumed to be pseudo-Fickian in PBS solution. The CS/PVA-based hydrogel composite exhibited good properties as a drug delivery system. © 2017 Elsevier B.V.
URI: https://ir.swu.ac.th/jspui/handle/123456789/12809
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85029565930&doi=10.1016%2fj.ijbiomac.2017.09.002&partnerID=40&md5=d9660695ce42d1ae6543e4ca838dd553
ISSN: 1418130
Appears in Collections:Scopus 1983-2021

Files in This Item:
There are no files associated with this item.


Items in SWU repository are protected by copyright, with all rights reserved, unless otherwise indicated.