Please use this identifier to cite or link to this item: https://ir.swu.ac.th/jspui/handle/123456789/12790
ชื่อเรื่อง: Association of herbal and dietary supplements with progression and complications of chronic kidney disease: A prospective cohort study
ผู้แต่ง: Tangkiatkumjai M.
Boardman H.
Praditpornsilpa K.
Walker D.-M.
Keywords: diclofenac
herbaceous agent
nonsteroid antiinflammatory agent
prostaglandin synthase inhibitor
adult
Article
chronic kidney disease
cohort analysis
controlled study
creatinine blood level
diet supplementation
disease course
disease severity
electrolyte blood level
end stage renal disease
female
glomerulus filtration rate
herbal medicine
human
hyperkalemia
hyperphosphatemia
kidney function
major clinical study
male
microalbuminuria
outcome assessment
outpatient
phosphate blood level
potassium blood level
priority journal
prospective study
proteinuria
renal replacement therapy
Thai (people)
วันที่เผยแพร่: 2015
บทคัดย่อ: Aim To determine associations between herbal and dietary supplement (HDS) use and the progression of chronic kidney disease (CKD), and associations of HDS with uncontrolled hyperphosphataemia in patients with CKD. Method The cohort study recruited 406 Thai outpatients with stage 3-5 CKD from two kidney clinics of which 357 were followed up over 12 months. Patients receiving renal replacement therapy prior to recruitment were excluded. Participants were interviewed regarding their HDS use, dietary intake and conventional medication adherence using a questionnaire. The primary outcome was a composite of a decline of at least 5 mL/min per 1.73 m2 per year of estimated glomerular filtration rate and end stage renal disease. Serum creatinine, serum levels of potassium and phosphate were extracted from their medical notes over the 12 months. χ2 tests and multiple logistic regression analyses were performed to ascertain any associations. Results Despite no association between HDS and the progression of CKD over a one-year period (adjusted odds ratio (OR) 1.16, 95% confidence interval (CI) 0.66-2.03), two patients had acute kidney injury, which may be related to an unknown Chinese herbal medicine, or river spiderwort combined with diclofenac reported in the medical notes. The use of HDS was associated with uncontrolled hyperphosphataemia (adjusted OR 3.53, 95%CI 1.20-10.43). Conclusions The findings suggest that HDS are likely to be related to acute kidney injury rather than the progression of CKD in Thai patients with CKD. The products were associated with uncontrolled hyperphosphataemia. Patients who have CKD and use HDS should be closely monitored regarding their kidney function and electrolytes. © 2015 Asian Pacific Society of Nephrology.
URI: https://ir.swu.ac.th/jspui/handle/123456789/12790
https://www.scopus.com/inward/record.uri?eid=2-s2.0-84941277608&doi=10.1111%2fnep.12531&partnerID=40&md5=07f03e1337ae6267c0bb8e8645740de9
ISSN: 13205358
Appears in Collections:Scopus 1983-2021

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