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https://ir.swu.ac.th/jspui/handle/123456789/12627| Title: | Vessel tortuosity cutoff values using the modified Roptool may predict need for treatment in retinopathy of prematurity |
| Authors: | Lertjirachai I. Stem M.S. Moysidis S.N. Koulisis N. Capone A. Jr. Drenser K.A. Trese M.T. |
| Keywords: | arteriole Article clinical article controlled study data analysis software diagnostic accuracy female highest vessel tortuosity human image analysis infant low level laser therapy male mean vessel tortuosity medical photography prediction prematurity priority journal quantitative analysis receiver operating characteristic reference value retina blood vessel retinal vessel tortuosity retrolental fibroplasia retrospective study sensitivity and specificity statistical significance treatment indication venule computer assisted diagnosis follow up newborn pathology predictive value procedures reproducibility retrolental fibroplasia Diagnosis, Computer-Assisted Female Follow-Up Studies Humans Infant, Newborn Laser Therapy Male Predictive Value of Tests Reproducibility of Results Retinal Vessels Retinopathy of Prematurity Retrospective Studies ROC Curve |
| Issue Date: | 2019 |
| Abstract: | BACKGROUND AND OBJECTIVE: To quantify vessel tortuosity among infants with retinopathy of prematurity (ROP). PATIENTS AND METHODS: This was a retrospective study including 61 RetCam images from 33 infants. The laser treatment (LT) group included 17 infants who underwent laser for ROP. The no-treatment (NT) group included 16 infants. The modified ROPtool was used to calculate mean vessel tortuosity (MVT) and highest vessel tortuosity (HVT) for the participants and for the standard plus disease photograph from the Early Treatment for Retinopathy of Prematurity (ETROP) study. RESULTS: The median MVT was 1.226 versus 1.056 for the LT and NT groups, respectively (P < .001). The median HVT was 1.346 versus 1.088 (P < .001). An MVT of 1.124 was 96.7% sensitive and 100% specific for identifying infants with treatment-requiring ROP. Both MVT and HVT cutoff values correctly captured plus disease in the standard ETROP trial photograph. CONCLUSION: The modified ROPtool can be used to identify infants who have treatment-requiring ROP with a high level of sensitivity and specificity. © 2019 Slack Incorporated. All rights reserved. |
| URI: | https://ir.swu.ac.th/jspui/handle/123456789/12627 https://www.scopus.com/inward/record.uri?eid=2-s2.0-85065081998&doi=10.3928%2f23258160-20190401-03&partnerID=40&md5=5d7456575424bceacafb374cd837a17d |
| ISSN: | 23258160 |
| Appears in Collections: | Scopus 1983-2021 |
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