Please use this identifier to cite or link to this item: https://ir.swu.ac.th/jspui/handle/123456789/12008
ชื่อเรื่อง: The effect of age, sex, race/ethnicity, health insurance, and food specific serum immunoglobulin E on outcomes of oral food challenges
ผู้แต่ง: Dang A.T.
Chundi P.K.
Mousa N.A.
Beyer A.I.
Chansakulporn S.
Venter C.
Mersha T.B.
Assa'ad A.H.
Keywords: immunoglobulin E
adolescent
adult
age
angioneurotic edema
Article
child
clinical outcome
controlled study
coughing
diagnostic procedure
egg allergy
erythema
ethnicity
female
food
health insurance
human
immunoglobulin blood level
major clinical study
male
medicaid
milk allergy
nausea
oral food challenge
peanut allergy
preschool child
priority journal
pruritus
race
retrospective study
rhinorrhea
sex difference
urticaria
vomiting
วันที่เผยแพร่: 2020
บทคัดย่อ: Background: Although oral food challenge (OFC) is an important clinical procedure for diagnosing food allergy, there is a paucity of literature on the outcome of the procedure and specifically the patients on whom the procedure is performed from the aspects of their age, sex, race/ethnicity, health insurance status, and serum specific IgE to the food tested. Objective: We aimed to review results of OFC and determine the impact of patient age, sex, race/ethnicity, insurance status, private or public, and food specific serum IgE on the outcome of OFC. Methods: A retrospective chart review was performed of patients undergoing OFCs at a children's hospital outpatient allergy clinic over a two-year period. The outcome of OFC was allergic or non-allergic based on determination and documentation by the treating physician. A logistic regression model was built to determine the association between the OFC outcomes, age, and symptoms at the time of OFC. A Chi-square analysis was performed to check for any significant relationship between the OFC outcome and age when stratified by insurance status. Results: Five hundred and eight children underwent 641 OFCs. Twenty nine percent of OFCs had an allergic outcome with the most commonly challenged foods being peanuts, eggs, and milk. Patient age and gender, when stratified by insurance status, did not have a significant effect on OFC outcomes. Serum IgE to peanuts and egg was significantly different between allergic OFC and non-allergic outcome. Vomiting and urticaria/angioedema correlated with an allergic OFC outcome. Conclusion: OFCs confirm the food allergy diagnosis in about one-third of patients tested, and they should continue to be used when possible for an accurate diagnosis. Age, sex, and insurance status do not have a significant association with the outcome of OFC and cannot be added as predictive factors. © 2020 The Author(s)
URI: https://ir.swu.ac.th/jspui/handle/123456789/12008
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85079413853&doi=10.1016%2fj.waojou.2020.100100&partnerID=40&md5=fba8fba4c4fa5fb3bac2a20b9ae2fb04
ISSN: 19394551
Appears in Collections:Scopus 1983-2021

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