dc.contributor.author |
Sangjarusvichai H. |
|
dc.contributor.author |
Dungchai W. |
|
dc.contributor.author |
Siangproh W. |
|
dc.contributor.author |
Chailapakul O. |
|
dc.date.accessioned |
2021-04-05T04:32:10Z |
|
dc.date.available |
2021-04-05T04:32:10Z |
|
dc.date.issued |
2009 |
|
dc.identifier.issn |
399140 |
|
dc.identifier.other |
2-s2.0-67650456893 |
|
dc.identifier.uri |
https://ir.swu.ac.th/jspui/handle/123456789/14943 |
|
dc.identifier.uri |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-67650456893&doi=10.1016%2fj.talanta.2009.02.026&partnerID=40&md5=eb675944a873a2770a4ef052840840d7 |
|
dc.description.abstract |
In this report, we aimed to extend our previous efforts toward the evaluation of sulfonamides (SAs) with a boron-doped diamond (BDD) electrode. We improved this method by reducing the analysis time using a monolithic column coupled with amperometric detection to determine seven sulfonamides (sulfaguanidine, sulfadiazine, sulfamethazine, sulfamonomethoxine, sulfamethoxazole, sulfadimethoxine and sulfaquinoxaline). Because of its rapid separation, low back-pressure and high separation efficiency compared to a particle-packed column, a monolithic column (100 mm × 4.6 mm) was used for sulfonamide separation. Chromatographic separation was performed in less than 8 min. The analysis was carried out using phosphate buffer (0.1 M, pH 3): acetonitrile: methanol in a ratio of 80:15:5 (v/v/v) as the mobile phase with a flow rate of 1.5 mL min-1. The optimal detection potential using hydrodynamic voltammetry was found to be 1.2 V versus Ag/AgCl. The method was applied to determine seven sulfonamides in shrimp after sample preparation by solid-phase extraction. The recoveries of the sulfonamides in spiked shrimp samples at 1.5, 5 and 10 μg g-1 were in the range of 81.7 to 97.5% with a relative standard deviation (R.S.D.) between 1.0 and 4.6%. Our methodology produced results that were highly correlated with HPLC-MS data. Therefore, we propose a method that can be used for the rapid, selective and sensitive evaluation of sulfonamides in contaminated food. © 2009 Elsevier B.V. All rights reserved. |
|
dc.subject |
Amides |
|
dc.subject |
Boolean functions |
|
dc.subject |
Drug products |
|
dc.subject |
Electrodes |
|
dc.subject |
High performance liquid chromatography |
|
dc.subject |
Phase separation |
|
dc.subject |
Shellfish |
|
dc.subject |
Amperometric detection |
|
dc.subject |
Boron doped diamond electrodes |
|
dc.subject |
Chromatographic separations |
|
dc.subject |
High separation efficiency |
|
dc.subject |
Highly sensitive detections |
|
dc.subject |
Monolithic columns |
|
dc.subject |
Relative standard deviation (R.S.D.) |
|
dc.subject |
Sulfonamides |
|
dc.subject |
Sulfur compounds |
|
dc.title |
Rapid separation and highly sensitive detection methodology for sulfonamides in shrimp using a monolithic column coupled with BDD amperometric detection |
|
dc.type |
Article |
|
dc.rights.holder |
Scopus |
|
dc.identifier.bibliograpycitation |
Talanta. Vol 79, No.4 (2009), p.1036-1041 |
|
dc.identifier.doi |
10.1016/j.talanta.2009.02.026 |
|