| dc.contributor.author |
Gornall K.C. |
|
| dc.contributor.author |
Samosorn S. |
|
| dc.contributor.author |
Tanwirat B. |
|
| dc.contributor.author |
Suksamrarn A. |
|
| dc.contributor.author |
Bremner J.B. |
|
| dc.contributor.author |
Kelso M.J. |
|
| dc.contributor.author |
Beck J.L. |
|
| dc.date.accessioned |
2021-04-05T03:36:24Z |
|
| dc.date.available |
2021-04-05T03:36:24Z |
|
| dc.date.issued |
2010 |
|
| dc.identifier.issn |
13597345 |
|
| dc.identifier.other |
2-s2.0-77956046998 |
|
| dc.identifier.uri |
https://ir.swu.ac.th/jspui/handle/123456789/14678 |
|
| dc.identifier.uri |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-77956046998&doi=10.1039%2fc0cc01933j&partnerID=40&md5=d896c3fd3d71430da27ee1792567e721 |
|
| dc.description.abstract |
ESI mass spectrometry was used to assess the binding of 13-substituted, 5-nitro-2-phenylindolyl- and 2-naphthalenyl-based berberine derivatives to inter- and intramolecular G-quadruplex DNA molecules. In contrast with the parent berberine, the compounds showed selectivity for quadruplex over duplex DNA and stabilised the quadruplex structure. They represent a new class of quadruplex DNA-selective ligands. © 2010 The Royal Society of Chemistry. |
|
| dc.subject |
2 naphthalenyl |
|
| dc.subject |
5 nitro 2 phenylindolyl |
|
| dc.subject |
berberine derivative |
|
| dc.subject |
daunorubicin |
|
| dc.subject |
double stranded DNA |
|
| dc.subject |
guanine quadruplex |
|
| dc.subject |
unclassified drug |
|
| dc.subject |
article |
|
| dc.subject |
DNA binding |
|
| dc.subject |
DNA sequence |
|
| dc.subject |
DNA structure |
|
| dc.subject |
electrospray mass spectrometry |
|
| dc.subject |
ligand binding |
|
| dc.subject |
molecule |
|
| dc.title |
A mass spectrometric investigation of novel quadruplex DNA-selective berberine derivatives |
|
| dc.type |
Article |
|
| dc.rights.holder |
Scopus |
|
| dc.identifier.bibliograpycitation |
Chemical Communications. Vol 46, No.35 (2010), p.6602-6604 |
|
| dc.identifier.doi |
10.1039/c0cc01933j |
|