| dc.contributor.author |
Nakamura Y. |
|
| dc.contributor.author |
He X. |
|
| dc.contributor.author |
Kato H. |
|
| dc.contributor.author |
Wakitani S. |
|
| dc.contributor.author |
Kobayashi T. |
|
| dc.contributor.author |
Watanabe S. |
|
| dc.contributor.author |
Iida A. |
|
| dc.contributor.author |
Tahara H. |
|
| dc.contributor.author |
Warman M.L. |
|
| dc.contributor.author |
Watanapokasin R. |
|
| dc.contributor.author |
Postlethwait J.H. |
|
| dc.date.accessioned |
2021-04-05T03:34:39Z |
|
| dc.date.available |
2021-04-05T03:34:39Z |
|
| dc.date.issued |
2012 |
|
| dc.identifier.issn |
2732289 |
|
| dc.identifier.other |
2-s2.0-84856260583 |
|
| dc.identifier.uri |
https://ir.swu.ac.th/jspui/handle/123456789/14402 |
|
| dc.identifier.uri |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-84856260583&doi=10.1007%2fs12010-011-9404-y&partnerID=40&md5=b7c62c3c83efc0cb97c7912a0ba81b75 |
|
| dc.description.abstract |
MicroRNA-140 (miR-140) is specifically expressed in developing cartilage tissues. We have previously reported that miR-140 plays an important role during palatal cartilage development by modulating platelet-derived growth factor receptor alpha (pdgfra) in zebrafish. However, the regulatory mechanism of miR-140 in cartilage is still unknown. Using developing zebrafish, sox9a mutant (sox9a-/-) and sox9b mutant (sox9b-/-) zebrafish and SOX9 small interfering RNA in human chondrocytes, T/C-28 cells, we found that miR-140 is regulated by the cartilage master transcription regulator Sox9 in zebrafish and mammalian cells. © 2011 Springer Science+Business Media, LLC. |
|
| dc.subject |
In situ hybridization |
|
| dc.subject |
MicroRNA-140 (miR-140) |
|
| dc.subject |
RT-PCR |
|
| dc.subject |
siRNA |
|
| dc.subject |
Sox9 |
|
| dc.subject |
T/C-28 |
|
| dc.subject |
Zebrafish |
|
| dc.subject |
Mammals |
|
| dc.subject |
Polymerase chain reaction |
|
| dc.subject |
RNA |
|
| dc.subject |
Tissue |
|
| dc.subject |
Cartilage |
|
| dc.subject |
microRNA |
|
| dc.subject |
microRNA 140 |
|
| dc.subject |
mutant protein |
|
| dc.subject |
platelet derived growth factor alpha receptor |
|
| dc.subject |
small interfering RNA |
|
| dc.subject |
transcription factor Sox9 |
|
| dc.subject |
unclassified drug |
|
| dc.subject |
animal experiment |
|
| dc.subject |
article |
|
| dc.subject |
cartilage |
|
| dc.subject |
cartilage cell |
|
| dc.subject |
controlled study |
|
| dc.subject |
human |
|
| dc.subject |
human cell |
|
| dc.subject |
in situ hybridization |
|
| dc.subject |
nonhuman |
|
| dc.subject |
protein expression |
|
| dc.subject |
reverse transcription polymerase chain reaction |
|
| dc.subject |
transcription regulation |
|
| dc.subject |
zebra fish |
|
| dc.subject |
Animals |
|
| dc.subject |
Binding Sites |
|
| dc.subject |
Cartilage |
|
| dc.subject |
Chondrocytes |
|
| dc.subject |
Chondrogenesis |
|
| dc.subject |
Embryonic Development |
|
| dc.subject |
Gene Expression Regulation, Developmental |
|
| dc.subject |
Humans |
|
| dc.subject |
In Situ Hybridization |
|
| dc.subject |
MicroRNAs |
|
| dc.subject |
Phylogeny |
|
| dc.subject |
Protein Binding |
|
| dc.subject |
RNA, Small Interfering |
|
| dc.subject |
SOX9 Transcription Factor |
|
| dc.subject |
Ubiquitin-Protein Ligases |
|
| dc.subject |
Zebrafish |
|
| dc.subject |
Danio rerio |
|
| dc.subject |
Mammalia |
|
| dc.title |
Sox9 is upstream of microRNA-140 in cartilage |
|
| dc.type |
Article |
|
| dc.rights.holder |
Scopus |
|
| dc.identifier.bibliograpycitation |
Applied Biochemistry and Biotechnology. Vol 166, No.1 (2012), p.64-71 |
|
| dc.identifier.doi |
10.1007/s12010-011-9404-y |
|