dc.contributor.author |
Tangsirapat V. |
|
dc.contributor.author |
Wongta K. |
|
dc.contributor.author |
Chakrapan Na Ayudhya K. |
|
dc.contributor.author |
Chakrapan Na Ayudhya V. |
|
dc.contributor.author |
Sookpotarom P. |
|
dc.date.accessioned |
2021-04-05T03:04:46Z |
|
dc.date.available |
2021-04-05T03:04:46Z |
|
dc.date.issued |
2019 |
|
dc.identifier.issn |
22102612 |
|
dc.identifier.other |
2-s2.0-85074370143 |
|
dc.identifier.uri |
https://ir.swu.ac.th/jspui/handle/123456789/12656 |
|
dc.identifier.uri |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85074370143&doi=10.1016%2fj.ijscr.2019.10.073&partnerID=40&md5=5b9a16290d25b029551b8842ea027afa |
|
dc.description.abstract |
Background: Pancreatic neuroendocrine tumors (PNETs) are rarely found and the majority of PNETs are nonfunctioning. At present, a patient with pancreatic neuroendocrine tumor (PNET), lymphoma, and squamous cell carcinoma (SCC) occurring simultaneously has not been reported. We presented all these three primary cancers in a same patient. Case presentation: A 51-year-old male presented with a right testicular mass for four months. He underwent right orchidectomy, and the patient was diagnosed malignant diffuse large B-cell lymphoma. Consequently, CHOP regimen and intrathecal methotrexate were given as treatment. During the metastasis work up, a hypodense lesion at the tail of pancreas was found. Distal pancreatectomy and splenectomy were completed, and the pathological report revealed PNET. Eighteen months later, the patient developed a symptom of odynophagia, direct laryngoscopy was performed and a mass at the left arytenoid was found. The biopsy was done and confirmed the diagnosis of SCC. The patient went through concurrent chemo-radiation with a complete response. Currently the patient remains in a complete remission of all three cancers. Discussion: As the patient had non-functioning PNET and was symptom-free, the diagnosis would have not been discovered without the metastasis workup of lymphoma. Although non-functioning PNET less than 2 cm can be safely observed, the tumor was 4.3 × 1.3 cm and adenocarcinoma was suspected, so the patient underwent the surgery. Conclusion: Although many cases with multiple primary cancers have been published, a case of patient with PNET, lymphoma, and SCC occurring as primary cancers has not been yet reported. © 2019 The Author(s) |
|
dc.subject |
CD20 antigen |
|
dc.subject |
Ki 67 antigen |
|
dc.subject |
methotrexate |
|
dc.subject |
neuron specific enolase |
|
dc.subject |
receptor type tyrosine protein phosphatase C |
|
dc.subject |
synaptophysin |
|
dc.subject |
adult |
|
dc.subject |
antigen expression |
|
dc.subject |
Article |
|
dc.subject |
axillary lymph node |
|
dc.subject |
cancer adjuvant therapy |
|
dc.subject |
cancer diagnosis |
|
dc.subject |
cancer regression |
|
dc.subject |
cancer staging |
|
dc.subject |
case report |
|
dc.subject |
chemoradiotherapy |
|
dc.subject |
clinical article |
|
dc.subject |
computer assisted tomography |
|
dc.subject |
diabetes mellitus |
|
dc.subject |
diffuse large B cell lymphoma |
|
dc.subject |
distal pancreatectomy |
|
dc.subject |
human |
|
dc.subject |
hypertension |
|
dc.subject |
hypopharynx squamous cell carcinoma |
|
dc.subject |
immunohistochemistry |
|
dc.subject |
incidental finding |
|
dc.subject |
inguinal region |
|
dc.subject |
lymphadenopathy |
|
dc.subject |
male |
|
dc.subject |
medical history |
|
dc.subject |
middle aged |
|
dc.subject |
odynophagia |
|
dc.subject |
orchiectomy |
|
dc.subject |
pancreas islet cell tumor |
|
dc.subject |
priority journal |
|
dc.subject |
radiation response |
|
dc.subject |
smoking |
|
dc.subject |
splenectomy |
|
dc.subject |
surgical margin |
|
dc.subject |
testis tumor |
|
dc.title |
Pancreatic neuroendocrine tumor, lymphoma, and squamous cell carcinoma of hypopharynx; A case report of three primary cancers in one patient |
|
dc.type |
Article |
|
dc.rights.holder |
Scopus |
|
dc.identifier.bibliograpycitation |
International Journal of Surgery Case Reports. Vol 65, (2019), p.111-114 |
|
dc.identifier.doi |
10.1016/j.ijscr.2019.10.073 |
|