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Browsing by Subject "circadian rhythm"

Browsing by Subject "circadian rhythm"

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  • A noradrenergic sensitive endogenous clock is present in the rat pineal gland 
    Wongchitrat P.; Felder-Schmittbuhl M.-P.; Govitrapong P.; Phansuwan-Pujito P.; Simonneaux V. (2011)
    The aim of this study was to examine the occurrence of endogenous oscillations of Per1, Per2, Bmal1 and Rev-erbα genes in rat pineal explants and to investigate their regulation by adrenergic ligands. Our results show a ...
  • Development of clock genes expression in rat hippocampus 
    Pramong R.; Wongchitrat P.; Govitrapong P.; Phansuwan-Pujito P. (2015)
    Background: The circadian rhythms in the suprachiasmatic nucleus (SCN), a central clock, are generated by autoregulatory network composed of clock genes that encode transcriptional factors. There is a gradual development ...
  • Effect of amphetamine on the clock gene expression in rat striatum 
    Wongchitrat P.; Mukda S.; Phansuwan-Pujito P.; Govitrapong P. (2013)
    •Chronic d-amphetamine altered the daily pattern of clock genes expressions in the rat striatum.•Bmal1 was shifted from a diurnal to a nocturnal pattern by d-amphetamine treatments.•d-Amphetamine altered the Rev-erbα rhythm ...
  • Endogenous rhythmicity of Bmal1 and Rev-erbα in the hamster pineal gland is not driven by norepinephrine 
    Wongchitrat P.; Felder-Schmittbuhl M.-P.; Phansuwan-Pujito P.; Pévet P.; Simonneaux V. (2009)
    Pineal melatonin is synthesized with daily and seasonal rhythms following the hypothalamic clock-driven release of norepinephrine (NE). The pineal gland of rats and mice, like the biological clock, expresses a number of ...
  • Pineal opioid receptors and analgesic action of melatonin 
    Ebadi M.; Govitrapong P.; Phansuwan-Pujito P.; Nelson F.; Reiter R.J. (1998)
    Physicians have noted since antiquity that their patients complained of less pain and required fewer analgesics at night times. In most species, including the humans, the circulating levels of melatonin, a substance with ...
  • Relationship between circadian clock genes and the neurotrophic factor genes in rat hippocampus 
    Pramong R.; Govitrapong P.; Phansuwan-Pujito P. (2017)
    Background: The hippocampus, a key brain area for learning and memory, can express clock genes with circadian fashion. The neurotrophic factors are important for cognitive function in the hippocampus. The expression of ...
  • The expression of Per1 and Aa-nat genes in the pineal gland of postnatal rats 
    Wongchitrat P.; Govitrapong P.; Phansuwan-Pujito P. (2012)
    Background: The circadian rhythm of melatonin synthesis is controlled by the master clock, suprachiasmatic nucleus (SCN).The level of melatonin changes throughout the aging process. The SCN's rhythm is driven by autoregulatory ...