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Barakol extracted from cassia siamea stimulates chloride secretion in rat colon

Deachapunya C.; Poonyachoti S.; Thongsaard W.; Krishnamra N. (2005)

Barakol is a purified extract of Cassia siamea, a plant that has been used as a laxative in traditional medicine. In this study, the effect of barakol on anion transport across the rat colon epithelium was investigated. ...
Barakol suppresses norepinephrine-induced inhibition of spontaneous longitudinal smooth muscle contractions in isolated rat small intestine

Deachapunya C.; Thongsaard W.; Poonyachoti S. (2005)

The present study aimed to investigate the purgative effects of barakol, the purified extract of Cassia siamea Lam., on the longitudinal smooth muscle contractions of the rat ileum. The extract increased the force of ...
Barakol, a natural anxiolytic inhibits striatal dopamine release but not uptake in vitro

Thongsaard W.; Pongsakorn S.; Sudsuang R.; Bennett G.W.; Kendall D.A.; Marsden C.A. (1997)

The present study investigated the effects of barakol on the in vitro release of endogenous and radiolabelled dopamine from rat striatal slices in comparison with the dopamine receptor agonist, quinelorane dihydrochloride ...
Barakol: A potential anxiolytic extracted from Cassia siamea

Thongsaard W.; Deachapunya C.; Pongsakorn S.; Boyd E.A.; Bennett G.W.; Marsden C.A. (1996)

The behavioural effects of an extract of Cassia siamea, a plant used in Thai traditional medicine, and barakol, its active chemical, were studied on an elevated plus-maze compared with diazepam. An aqueous extract of C. ...
Behavioral effects of acute and chronic oral administration of barakol in rats.

Deachapunya C.; Thongsaard W. (2009)

INTRODUCTION: Barakol, an active constituent extracted from Cassia siamea, has been shown to have anxiolytic effects similar to diazepam when treated intraperitoneally. OBJECTIVE: Acute and chronic oral administrations of ...
Determination of barakol extracted from Cassia siamea by HPLC with electrochemical detection

Thongsaard W.; Chainakul S.; Bennett G.W.; Marsden C.A. (2001)

Barakol is an active compound extracted from the leaves and flowers of the plant called Cassia siamea grown widely in Southeast Asia. There have been a number of reports on the chemical structure and properties of this ...
Stability of barakol under hydrolytic stress conditions and its major degradation product

Chantong B.; Wongtongtair S.; Nusuetrong P.; Sotanaphun U.; Chaichantipyuth C.; Meksuriyen D. (2009)

The aim of the present study was to investigate the stability of barakol, an anxiolytic constituent extracted from leaves of Senna siamea (Lam.) Irwin & Barneby (syn. Cassia siamea Lam.), under the International ...

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