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Browsing by Subject "autophagosome"

Browsing by Subject "autophagosome"

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  • Autophagy in epithelial homeostasis and defense 
    Sukseree S.; Eckhart L.; Tschachler E.; Watanapokasin R. (2013)
    Autophagy delivers protein aggregates, damaged organelles and intracellular microorganisms to the lysosome for degradation. The epidermis and other epithelia show significant levels of autophagy, however, the functions of ...
  • Autophagy in the thymic epithelium is dispensable for the development of self-tolerance in a novel mouse model 
    Sukseree S.; Mildner M.; Rossiter H.; Pammer J.; Zhang C.-F.; Watanapokasin R.; Tschachler E.; Eckhart L. (2012)
    The thymic epithelium plays critical roles in the positive and negative selection of T cells. Recently, it was proposed that autophagy in thymic epithelial cells is essential for the induction of T cell tolerance to self ...
  • Epidermal keratinocytes form a functional skin barrier in the absence of Atg7 dependent autophagy 
    Rossiter H.; König U.; Barresi C.; Buchberger M.; Ghannadan M.; Zhang C.-F.; Mlitz V.; Gmeiner R.; Sukseree S.; Födinger D.; Eckhart L.; Tschachler E. (2013)
    Background: Cornification of keratinocytes involves the degradation of intracellular constituents which has led to the hypothesis that autophagy plays a role in this process. Mice, in which essential autophagy-related genes ...