Browsing by Subject "Cell Cycle Checkpoints"

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Methanolic extract from sea cucumber, Holothuria scabra, induces apoptosis and suppresses metastasis of PC3 prostate cancer cells modulated by MAPK signaling pathway

Pranweerapaiboon K.; Noonong K.; Apisawetakan S.; Sobhon P.; Chaithirayanon K. (2021)

Sea cucumber, Holothuria scabra, is a well-known traditional Asian medicine that has been used for suppressing inflammation, promoting wound healing, and improving immunity. Moreover, previous studies demonstrated that the ...
Sensory acceptable equivalent doses of β-phenylethyl isothiocyanate (PEITC) induce cell cycle arrest and retard the growth of p53 mutated oral cancer in vitro and in vivo

Lam-Ubol A.; Fitzgerald A.L.; Ritdej A.; Phonyiam T.; Zhang H.; Myers J.N.; Huang P.; Trachootham D. (2018)

High doses of β-phenylethyl isothiocyanate (PEITC), a phytochemical in cruciferous vegetables, are not feasible for consumption due to a strong mouth-tingling effect. This study investigated the anti-cancer effect of PEITC ...

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