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Browsing by Subject "1,4 naphthoquinone derivative"

Browsing by Subject "1,4 naphthoquinone derivative"

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  • Aromatase inhibitory activity of 1,4-naphthoquinone derivatives and QSAR study 
    Prachayasittikul V.; Pingaew R.; Worachartcheewan A.; Sitthimonchai S.; Nantasenamat C.; Prachayasittikul S.; Ruchirawat S.; Prachayasittikul V. (2017)
    A series of 2-amino(chloro)-3-chloro-1,4-naphthoquinone derivatives (1-11) were investigated for their aromatase inhibitory activities. 1,4-Naphthoquinones 1 and 4 were found to be the most potent compounds affording IC50 ...
  • Effect of 1,4-Napthoquinone Derivatives on Anti-proliferation and Apoptosis Induction in Skin and Lung Cancer Cells 
    Poomsaard S.; Sakdawattanakul I.; Ackapronwong N.; Innajak S.; Poorahong W.; Pingaew R.; Visitsakulchai K.; Watanapokasin R. (2022)
    Background: Cancer is a major public health concern around the world. Nowadays, standard therapy in combination with targeted therapy are being used for cancer treatment, but these therapeutics show side effects or unwanted ...
  • Novel 1,4-naphthoquinone-based sulfonamides: Synthesis, QSAR, anticancer and antimalarial studies 
    Pingaew R.; Prachayasittikul V.; Worachartcheewan A.; Nantasenamat C.; Prachayasittikul S.; Ruchirawat S.; Prachayasittikul V. (2015)
    A novel series of 1,4-naphthoquinones (33-44) tethered by open and closed chain sulfonamide moieties were designed, synthesized and evaluated for their cytotoxic and antimalarial activities. All quinone-sulfonamide derivatives ...
  • Synthesis, anticancer activity and QSAR study of 1,4-naphthoquinone derivatives 
    Prachayasittikul V.; Pingaew R.; Worachartcheewan A.; Nantasenamat C.; Prachayasittikul S.; Ruchirawat S.; Prachayasittikul V. (2014)
    A series of 2-substituted amino-3-chloro-1,4-naphthoquinone derivatives (3-12) were synthesized as anticancer agents and tested against four cancer cell lines including HepG2, HuCCA-1, A549 and MOLT-3. The most potent ...