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Browsing by Author "Pakakasama S."

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Allogeneic hematopoietic stem cell transplantation for children with severe aplastic anemia

Hutspardol S.; Sirachainan N.; Anurathapan U.; Pakakasama S.; Songdej D.; Chuansumrit A.; Sirireung S.; Panthangkool W.; Hongeng S. (2013)

Objective: Allogeneic hematopoietic stem cell transplantation (allo-SCT) is a potentially curative treatment for severe aplastic anemia (SAA). This is a single institutional review to study the feasibility of using allo-SCT ...
Interphase-FISH screening for eight common rearrangements in pediatric B-cell precursor acute lymphoblastic leukemia

Hutspardol S.; Pakakasama S.; Kanta K.; Nuntakarn L.; Anurathapan U.; Sirachainan N.; Songdej D.; Sawangpanich R.; Tiyasirichokchai R.; Rerkamnuaychoke B.; Hongeng S. (2013)

Summary: Introduction: This is the first pilot study to screen multiple common genetic aberrations in B-cell precursor acute lymphoblastic leukemia (BCP-ALL). Methods: Thirty-two children with BCP-ALL were investigated for ...
NUDT15 genetic variants are related to thiopurine-induced neutropenia in Thai children with acute lymphoblastic leukemia

Puangpetch A.; Tiyasirichokchai R.; Pakakasama S.; Wiwattanakul S.; Anurathapan U.; Hongeng S.; Sukasem C. (2020)

Aim: 6-Mercaptopurine (6MP) is key to the treatment of acute lymphoblastic leukemia (ALL) as part of maintenance therapy. NUDT15 was identified as a novel thiopurine regulator conferring 6MP sensitivity. The aim of this ...
Tpmt*3c as a predictor of 6-mercaptopurine-induced myelotoxicity in thai children with acute lymphoblastic leukemia

Jantararoungtong T.; Wiwattanakul S.; Tiyasirichokchai R.; Prommas S.; Sukprasong R.; Koomdee N.; Jinda P.; Rachanakul J.; Nuntharadthanaphong N.; Pakakasama S.; Anurathapan U.; Hongeng S.; Sukasem C. (2021)

The response to 6-mercaptopurine (6-MP) can be altered by genetic polymorphisms in genes encoding drug-metabolizing enzymes and drug transporters. The purpose of this study was to investigate the association between genetic ...

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Browsing by Author "Pakakasama S."

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