Autophagy delivers protein aggregates, damaged organelles and intracellular microorganisms to the lysosome for degradation. The epidermis and other epithelia show significant levels of autophagy, however, the functions of ...

Background: Cornification of keratinocytes involves the degradation of intracellular constituents which has led to the hypothesis that autophagy plays a role in this process. Mice, in which essential autophagy-related genes ...