Please use this identifier to cite or link to this item: http://ir.swu.ac.th/jspui/handle/123456789/15164
Title: Ranitidine-enhanced 99m technetium pertechnetate imaging in children improves the sensitivity of identifying heterotopic gastric mucosa in Meckel's diverticulum
Authors: Rerksuppaphol S.
Hutson J.M.
Oliver M.R.
Keywords: cimetidine
pertechnetic acid tc 99m
ranitidine
diagnostic agent
histamine H2 receptor antagonist
radiopharmaceutical agent
ranitidine
adolescent
child
clinical article
contrast enhancement
diagnostic accuracy
drug safety
female
human
infant
male
Meckel diverticulum
priority journal
rectum hemorrhage
retrospective study
review
scintiscanning
stomach mucosa
article
choristoma
ileum disease
image enhancement
Meckel diverticulum
newborn
preschool child
sensitivity and specificity
Adolescent
Child
Child, Preschool
Choristoma
Female
Gastric Mucosa
Histamine H2 Antagonists
Humans
Ileal Diseases
Image Enhancement
Infant
Infant, Newborn
Male
Meckel Diverticulum
Radiopharmaceuticals
Ranitidine
Retrospective Studies
Sensitivity and Specificity
Sodium Pertechnetate Tc 99m
Issue Date: 2004
Abstract: Meckel's diverticulum is the most common congenital gastrointestinal anomaly. 99m Technetium pertechnetate imaging (Meckel's scan) is the best noninvasive method used to diagnose this condition when heterotopic gastric mucosa (HGM) is present. Although cimetidine enhancement has been shown to improve sensitivity of the Meckel's scan, ranitidine enhancement has also been advocated; however, this recommendation is based on unpublished data. Thirty-seven children with confirmed Meckel's diverticulum were reviewed retrospectively. Of eight children with HGM in the Meckel's diverticulum who presented with profuse rectal bleeding and underwent the conventional Meckel's scan, three of them (37.5%) had a false negative study. Ranitidine, when administered either intravenously or orally for 24 h prior to the Meckel's scan, enhanced the sensitivity of this test to 87.5% in our patient cohort.
URI: https://www.scopus.com/inward/record.uri?eid=2-s2.0-3242690710&doi=10.1007%2fs00383-004-1189-4&partnerID=40&md5=4255fcdab30dbc0a8475598e2ff0ed96
http://ir.swu.ac.th/jspui/handle/123456789/15164
ISSN: 1790358
Appears in Collections:Scopus 1983-2021

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