Please use this identifier to cite or link to this item: http://ir.swu.ac.th/jspui/handle/123456789/15100
Title: Ovulation block by Pueraria mirifica: A study of its endocrinological effect in female monkeys
Authors: Trisomboon H.
Malaivijitnond S.
Watanabe G.
Taya K.
Keywords: estradiol
follitropin
gonadotropin
inhibin
luteinizing hormone
phytoestrogen
progesterone
estradiol
follitropin
inhibin
luteinizing hormone
phytoestrogen
progesterone
animal experiment
article
dose response
estradiol blood level
feeding
female
follitropin blood level
gonadotropin blood level
herb
hormone blood level
hormone determination
luteinizing hormone blood level
Macaca
menstrual cycle
monkey
nonhuman
ovulation inhibition
peuraria mirifica
priority journal
progesterone blood level
Thailand
animal
blood
drug effect
menstrual cycle
Pueraria
Animals
Estradiol
Female
Follicle Stimulating Hormone
Inhibins
Luteinizing Hormone
Macaca fascicularis
Menstrual Cycle
Ovulation Inhibition
Phytoestrogens
Progesterone
Pueraria
Issue Date: 2005
Abstract: Pueraria mirifica (PM), a Thai herb containing phytoestrogens, may act as estrogen and disturb reproduction. To investigate the effect of PM on the menstrual cycle length and related hormones, nine adult female monkeys (Macaca fascicularis) were separated into three groups. Each group (n = 3) was fed with 10, 100, and 1000 mg/d of PM for three menstrual cycles. The menstrual cycle length increased significantly in mon-keys treated with PM-10 and PM-100 and disappeared completely in monkeys treated with PM-1000. Serum follicle stimulating hormone, luteinizing hormone, estradiol, progesterone, and ir-inhibin were lower during the treatment period in a dose-dependent manner. Changes in menstrual cycle length and the hormonal levels recovered during the post-treatment period only in monkeys treated with PM-10 and PM-100. PM greatly influences menstrual cycles and may suppress ovulation by lowering serum levels of gonadotropins. © 2005 by Humana Press Inc. All rights of any nature whatsoever reserved.
URI: https://www.scopus.com/inward/record.uri?eid=2-s2.0-23844558954&partnerID=40&md5=f3e64118fd049acaf2790128179b757c
http://ir.swu.ac.th/jspui/handle/123456789/15100
ISSN: 1355008X
Appears in Collections:SCOPUS 1983-2021

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