Please use this identifier to cite or link to this item: http://ir.swu.ac.th/jspui/handle/123456789/14983
Title: Chemical structures and biological activities of rhamnolipids produced by Pseudomonas aeruginosa B189 isolated from milk factory waste
Authors: Thanomsub B.
Pumeechockchai W.
Limtrakul A.
Arunrattiyakorn P.
Petchleelaha W.
Nitoda T.
Kanzaki H.
Keywords: Anticancer
Biological activity
Biosurfactant
Glycolipid
Pseudomonas
Rhamnolipid
Bacteria
Cell culture
Lipids
Structure (composition)
Surface active agents
Tumors
Bacteriology
antineoplastic agent
biosurfactant
decanoic acid derivative
dodecyl sulfate sodium
levo rhamnopyranosyl levo rhamnopyranosyl beta hydroxydecanoyl beta hydroxydecanoate
levo rhamnopyranosyl levo rhamnopyranosyl beta hydroxydecanoyl beta hydroxydodecanoate
lipid
polysorbate 80
surfactant
unclassified drug
Bacteria
Bacteriology
Cell culture
Lipids
Structure (composition)
Surface active agents
Tumors
bacterium
industrial waste
lipid
surfactant
waste treatment
animal cell
article
bacterium culture
bacterium isolate
biological activity
cancer cell culture
cell proliferation
chemical structure
controlled study
human
human cell
minimum inhibitory concentration
nonhuman
priority journal
Pseudomonas aeruginosa
Aedes
Animals
Antibiotics, Antineoplastic
Cell Line
Dairy Products
Glycolipids
Humans
Molecular Structure
Pseudomonas aeruginosa
Surface-Active Agents
Insecta
Pseudomonas aeruginosa
Issue Date: 2006
Abstract: The aim of this work was to study chemical structures and biological activities of rhamnolipids produced by Pseudomonas aeruginosa B189 isolated from milk factory waste. The culture produced two biosurfactants, a and b, which showed strong activity and were identified as l-rhamnopyranosyl-l-rhamnopyranosyl-β-hydroxydecanoyl-β-hydroxydecanoate or Rha-Rha C10-C10 and l-rhamnopyranosyl-l-rhamnopyranosyl-β-hydroxydecanoyl-β-hydroxydodecanoate or Rha-Rha C10-C12, respectively. Both compounds exhibited higher surfactant activities tested by the drop collapse test than several artificial surfactants such as SDS and Tween 80. Rhamnolipid a showed significant antiproliferative activity against human breast cancer cell line (MCF-7) at minimum inhibitory concentration (MIC) at 6.25 μg/mL while rhamnolipid b showed MIC against insect cell line C6/36 at 50 μg/mL. © 2005.
URI: https://www.scopus.com/inward/record.uri?eid=2-s2.0-33746227333&doi=10.1016%2fj.biortech.2005.10.029&partnerID=40&md5=21cf570463a46171570ce2b2b2e266ce
http://ir.swu.ac.th/jspui/handle/123456789/14983
ISSN: 9608524
Appears in Collections:SCOPUS 1983-2021

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