1. Srinakharinwirot University Institutional Repository
  2. Articles from Academic Databases : SCOPUS
  3. Scopus 1983-2021
Please use this identifier to cite or link to this item: https://ir.swu.ac.th/jspui/handle/123456789/14617
Full metadata record
DC FieldValueLanguage
dc.contributor.authorPrachayasittikul S.
dc.contributor.authorPingaew R.
dc.contributor.authorWorachartcheewan A.
dc.contributor.authorRuchirawat S.
dc.contributor.authorPrachayasittikul V.
dc.date.accessioned2021-04-05T03:35:59Z-
dc.date.available2021-04-05T03:35:59Z-
dc.date.issued2010
dc.identifier.issn16112156
dc.identifier.other2-s2.0-79151486711
dc.identifier.urihttps://ir.swu.ac.th/jspui/handle/123456789/14617-
dc.identifier.urihttps://www.scopus.com/inward/record.uri?eid=2-s2.0-79151486711&partnerID=40&md5=fd263d24f05e311169737354b58b6085
dc.description.abstractBioactivities of thiotetrahydropyridines were previously described. Herein, a novel bioactive sulfoxide analog; N-acetyl-2-(1-adamantylsulfoxo)-3-acetoxy-4-phenyl-6-hydroxy-1,2,3,6-tet rahydropyridine (3) from the deoxydative substitution of 4-phenylpyridine 1-oxide is reported. Its structure was elucidated using spectral data including 2D-NMR, MS, IR and UV. The sulfoxide 3 exhibited antibacterial activity against Moraxella catarrhalis and Streptococcus pyogenes with minimum inhibitory concentration of 128 and 256 μg/mL, respectively.
dc.subject1,2,3,6 tetrahydro 4 phenylpyridine
dc.subjectn acetyl 2(1 adamantylsulfoxo) 3 acetoxy 4 phenyl 6 hydroxy 1,2,3,6 tetrahydropyridine
dc.subjectsulfoxide
dc.subjectunclassified drug
dc.subjectantimicrobial activity
dc.subjectarticle
dc.subjectcontrolled study
dc.subjectdrug structure
dc.subjectdrug synthesis
dc.subjecthuman
dc.subjectinfrared radiation
dc.subjectmass spectrometry
dc.subjectminimum inhibitory concentration
dc.subjectMoraxella catarrhalis
dc.subjectnonhuman
dc.subjectnuclear magnetic resonance
dc.subjectStreptococcus pyogenes
dc.subjectthin layer chromatography
dc.subjectultraviolet radiation
dc.subjectMoraxella catarrhalis
dc.subjectStreptococcus pyogenes
dc.titleA new sulfoxide analog of 1,2,3,6-tetrahydrophenylpyridine and antimicrobial activity
dc.typeArticle
dc.rights.holderScopus
dc.identifier.bibliograpycitationEXCLI Journal. Vol 9, No. (2010), p.102-107
Appears in Collections:Scopus 1983-2021

Files in This Item:
There are no files associated with this item.
Show simple item record


Items in SWU repository are protected by copyright, with all rights reserved, unless otherwise indicated.