Please use this identifier to cite or link to this item: http://ir.swu.ac.th/jspui/handle/123456789/13975
Title: A microfluidic paper-based analytical device for rapid quantification of particulate chromium
Authors: Rattanarat P.
Dungchai W.
Cate D.M.
Siangproh W.
Volckens J.
Chailapakul O.
Henry C.S.
Keywords: 1 ,5-diphenylcarbazide
Airborne particulate matters
Instrumental techniques
Occupational exposure
Paper-based analytical devices
Particulate Matter
Proof of principles
Quantitative agreement
Analytic equipment
Chromium
Chromium compounds
Inductively coupled plasma
Inductively coupled plasma mass spectrometry
Microfluidics
1,5 diphenylcarbazone
carboxyl group
cerium
chromium
diphenylcarbazide
tetravalent cerium
unclassified drug
accuracy
article
chemical analysis
chemical parameters
color intensity
colorimetry
complex formation
concentration (parameters)
controlled study
elution
filter
general device
limit of detection
microfluidic analysis
molecular weight
paper based analytical device
particulate matter
priority journal
product development
quantitative analysis
reaction time
reproducibility
shelf life
temperature sensitivity
validation process
Chromium
Microfluidics
Paper-based analytical device
Particulate matter
Cerium
Chromium
Colorimetry
Diphenylcarbazide
Hydrogen-Ion Concentration
Microfluidic Analytical Techniques
Microwaves
Nitric Acid
Oxidation-Reduction
Paper
Particulate Matter
Polyethylenes
Quaternary Ammonium Compounds
Issue Date: 2013
Abstract: Occupational exposure to Cr is concerning because of its myriad of health effects. Assessing chromium exposure is also cost and resource intensive because the analysis typically uses sophisticated instrumental techniques like inductively coupled plasma-mass spectrometry (ICP-MS). Here, we report a novel, simple, inexpensive microfluidic paper-based analytical device (μPAD) for measuring total Cr in airborne particulate matter. In the μPAD, tetravalent cerium (Ce(IV)) was used in a pretreatment zone to oxidize all soluble Cr to Cr(VI). After elution to the detection zone, Cr(VI) reacts with 1,5-diphenylcarbazide (1,5-DPC) forming 1,5-diphenylcarbazone (DPCO) and Cr(III). The resulting Cr(III) forms a distinct purple colored complex with the DPCO. As proof-of-principle, particulate matter (PM) collected on a sample filter was analyzed with the μPAD to quantify the mass of total Cr. A log-linear working range (0.23-3.75μg; r2=0.998) between Cr and color intensity was obtained with a detection limit of 0.12μg. For validation, a certified reference containing multiple competing metals was analyzed. Quantitative agreement was obtained between known Cr levels in the sample and the Cr measured using the μPAD. © 2013 Elsevier B.V.
URI: https://www.scopus.com/inward/record.uri?eid=2-s2.0-84885224611&doi=10.1016%2fj.aca.2013.09.008&partnerID=40&md5=a7baa02b63fa9e1a8529f5d2b37e2479
http://ir.swu.ac.th/jspui/handle/123456789/13975
ISSN: 32670
Appears in Collections:Scopus 1983-2021

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