Please use this identifier to cite or link to this item: http://ir.swu.ac.th/jspui/handle/123456789/13774
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dc.contributor.authorNantaphol S.
dc.contributor.authorChailapakul O.
dc.contributor.authorSiangproh W.
dc.date.accessioned2021-04-05T03:26:21Z-
dc.date.available2021-04-05T03:26:21Z-
dc.date.issued2015
dc.identifier.issn9254005
dc.identifier.other2-s2.0-84910070201
dc.identifier.urihttps://www.scopus.com/inward/record.uri?eid=2-s2.0-84910070201&doi=10.1016%2fj.snb.2014.10.041&partnerID=40&md5=5aeb5c034c6b8e5e43d5215e2df5db33
dc.identifier.urihttp://ir.swu.ac.th/jspui/handle/123456789/13774-
dc.description.abstractFor the first time, a newly sensitive and simple method for the determination of cholesterol based on coupling of enzymatic assay and electrochemical detection has been developed. Silver nanoparticles modified glassy carbon electrode (AgNPs/GCE) was fabricated by electrochemical deposition technique and used as the working electrode. The electrochemical performances were investigated by cyclic voltammetry and chronoamperometry. Under the optimized conditions, a linear relationship between the reduction current and cholesterol concentration was found in the range of 3.9 mg/dL to 773.4 mg/dL with a detection limit of 0.99 mg/dL. The proposed method was applied to determine cholesterol in bovine serum. The recoveries obtained were within the range of 99.6-100.7%, which indicated that the presented method is applicable to determine cholesterol in bovine serum. In addition this electrochemical sensor displayed very high specificity to cholesterol with no observed interference from easily oxidizable species such as ascorbic acid and uric acid. All these excellent performances of the developed sensor indicated that this sensing platform could be easily extended to the detection of other important biomarkers. © 2014 Elsevier B.V. All rights reserved.
dc.subjectAscorbic acid
dc.subjectBody fluids
dc.subjectCarbon
dc.subjectCholesterol
dc.subjectChronoamperometry
dc.subjectCyclic voltammetry
dc.subjectElectrochemical sensors
dc.subjectGlass
dc.subjectGlass membrane electrodes
dc.subjectGlassy carbon
dc.subjectMammals
dc.subjectNanoparticles
dc.subjectReduction
dc.subjectSilver
dc.subjectVoltammetry
dc.subjectBovine serum
dc.subjectElectrochemical deposition
dc.subjectELectrochemical detection
dc.subjectElectrochemical performance
dc.subjectEnzymatic reaction
dc.subjectLinear relationships
dc.subjectModified glassy carbon electrode
dc.subjectSilver nanoparticles
dc.subjectChemical detection
dc.titleSensitive and selective electrochemical sensor using silver nanoparticles modified glassy carbon electrode for determination of cholesterol in bovine serum
dc.typeArticle
dc.rights.holderScopus
dc.identifier.bibliograpycitationSensors and Actuators, B: Chemical. Vol 207, No.Part A (2015), p.193-198
dc.identifier.doi10.1016/j.snb.2014.10.041
Appears in Collections:Scopus 1983-2021

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